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01On the stage of BCMACar-T and TCE compete on the same stage

Since the beginning of this year, news related to BCMA has come and gone.

In February, the BCMA Car-T therapeutic product Carvykti, which legendary creatures cooperated with Johnson & Johnson, was approved by the FDA of the United States, representing the success of China’s original innovation. At the beginning of August, Amgen quietly revealed that it had terminated the development of AMG701, the last BCMA drug in the pipeline. From having two double antibodies and an ADC in this target, to clearing the warehouse now, the change was embarrassing. Just two weeks later, it was reported that Johnson & Johnson’s CD3xBCMA double antibody Tecvayli obtained the conditional listing license of the European Union.

Why is the target of BCMA so hot?

BCMA (B-cell maturation antigen) is mainly expressed on the surface of mature B lymphocytes and plasma cells. When plasma cells in bone marrow proliferate abnormally, it can lead to multiple bone injuries and gradually develop into Multiple Myeloma, MM). MM mainly occurs in the elderly over 65 years old and is the second most common haematoma in the United States. In the past, the incidence rate in China was relatively low, accounting for about 20% of that in the United States. However, in recent years, with the economic development, the rate of medical treatment has increased, and the population is aging.The incidence of MM in China continues to rise, with data showing that it has reached 40-45% in the United States..

At present, MM is still a disease that is difficult to cure. Most patients will relapse more than once, and the remission time will be shortened after each relapse, which makes great demands on the treatment of relapsed or refractory MM (R/RMM). The study found that,Overexpression and activation of BCMA exist in both newly diagnosed and relapsed patients, making BCMA a high potential target for R/R MM drug development.2。

Since the first BCMA drug was launched in 2020, four drugs targeting this target have been approved, coveringADC、Car-TandCD3 double antibodyThree types (Table 1).

Table 1: BCMA targeted drugs on the market

Although the indications are all 4-or 5-line treatment of R/R MM, it can be clearly seen from the clinical efficacy that the latecomers have made continuous breakthroughs compared with the pioneers.. Compared with the first Car-T product Abecma, the second Car-T product Carvykti has greatly improved its effectiveness (ORR, CR, DoR) and CRS safety. The newly approved double antibody Tecvayli, although its response rate (ORR, CR) is not as good as that of Carvykti, is already comparable to that of Abecma, and it is also closely followed by Carvykti on DoR. As a "spot" drug, it can be said that it is threatening (Table 2).

Table 2: Clinical effects of drugs listed in 2：BCMA

In fact, whether Car-T or CD3 double antibody, the mechanism of action is to bring killer T cells to tumor cells expressed by BCMA, and destroy tumor cells through the killing function of T cells. The difference is that Car-T can increase the number of T cells by in vitro amplification, while CD3 double antibody mobilizes the existing T cells in the body, soCar-T can be administered once, with strong and lasting effect.However, CD3 antibody is similar to traditional medicine and needs to be given regularly. But at the same time, unlike Car-T’s personalized and customized therapy,CD3 antibody is a spot product, which has natural advantages in convenience, accessibility and production cost.These are also the challenges that Car-T therapy needs to overcome to achieve universality.

02 CD3xBCMA molecule: Different platform, different fate.

The concept of Bispecific T-cell engagers (TCE) was actually verified as early as 2014 through the listing of Amgen Blincyto(CD3xCD19 BiTE).. However, there has been no other breakthrough in these years. Until this year, TCE ushered in spring: in January, Immunocore Kimmtrak, gp100xCD3 fusion protein, FDA approved melanoma; In June, Roche Lunsumio, CD20xCD3 double antibody, the European Union approved follicular lymphoma; In August, Johnson & Johnson’s Tecvayli, BCMAxCD3, and the EU approved R/R MM. In the middle of the eight years, TCE has cut through the thorns on the road ahead.

Amgen BiTE? vs Janssen DuoBody?

Although Amgen’s development of CD3xBCMA failed in the end, as a pioneer of FIC in this field, it brought valuable experience and value, which can be said that although it was defeated, it was still glorious. In 2012, Amgen acquired Micromet, the inventor of BiTE technology, and in 2016, it repurchased CD3xBCMA BiTE, namely AMG420, from BI. AMG420 is the first batch of BCMA double antibodies that entered the clinic in 2015, and the phase I showed good curative effect.The potential of the concept of CD3xBCMA is verified.. However, due to the toxicity, the maximum dose is 400 ug/day, and the half-life is short, so it needs to be administered every day. Then, Amgen developed AMG701 based on BITE-HLT (half-life extension) technology, which started clinical practice in 2017. Although the frequency of drug administration was improved to once a week, the project was completely terminated in August this year because of its comprehensive effectiveness and safety competitiveness. Looking at Johnson & Johnson/Jansen, in 2012, we chose to cooperate with Genmab’s DuoBody double antibody platform, from which we hatched Tecwayli (CD3XBCMA). Tecvayli started clinical practice in May 2017, and started all the way. At the end of 2021, according to the results of clinical phase I/II MajesTEC-1, it submitted a listing application to the FDA. In August this year, it took the lead in obtaining a conditional listing permit in the European Union. On the BiTE platform based on scFv skeleton, Amgen has harvested Blincyto, but the following projects are all invincible; With the IgG skeleton provided by DuoBody platform, in the past two years, two consecutive double antibody molecules, RybRevont (Amivantamab, cmetxegfr) and Tecvayli, have been approved only by the speed of clinical I/II data and become popular fried chickens.Some people say that the success or failure of the double-resistance lies in the platform, which is exaggerated, but its importance is beyond doubt..

The challenge of TCE development vs the ability of double anti-platform

For CD3 TCE, overcoming the compatibility of effectiveness and safety and realizing an operable treatment window is the key to success. The CD3 used in AMG420 and AMG701 has the same high affinity as Blincyto. With the compact and flexible skeleton of BiTE, a tight immune synapse is formed between tumor cells and T cells, which leads to the strong activation of T cell function and the release of cytokines at the same time of tumor killing, resulting in a narrow treatment window. At the same time, due to the small molecular weight (~55 kD) and short half-life, BiTE needs to be administered daily. On the other hand, Tecvayli uses CD3 with high affinity, but its binding kinetics has been adjusted with high probability, and it is constructed in IgG skeleton (150 kD), which is beneficial to optimize the activation effect of T cells, thus achieving safe and effective clinical performance and once-a-week administration frequency. At the same time, recent studies have found that the killing function of T cells can be activated specifically by reducing the affinity of CD3, so as to avoid the association with the release of cytokines, thus expanding the treatment window, such as Abbv-383B, which is in clinical stage I of Abbvie.

Fig. 1: The mechanism of 1：TCE, and the molecular form 2 of BiTE (A) and DuoBody (B) double antibody platforms, while the other arm of CD3 TCE double antibody binds to tumor surface antigen. For hematomas, targets such as BCMA and CD20 have specific expression profiles and are limited to B lymphocytes. This specificity helps to achieve safety and contributes to the first success of TCE in hematological tumors. For solid tumors, tumor-associated antigens are often low-expressed in normal tissues. How to selectively bind to tumor sites and avoid the on-target off-tumor effect on normal tissues is a big challenge to TCE.At present, a mainstream strategy is to design antigen binding with high titer and weak affinity by optimizing the titer and affinity of antigen recognition arm, so as to improve the tendency of tumor tissue with high antigen expression.. On the other hand, in solid tumors, TCE needs to break through the tumor microenvironment of immunosuppression and the physical barrier of tumor matrix, so drug combination will be the trend, which also requires TCE to have a better treatment window and safety. The design and consideration of TCE are quite complicated, 7,8, and this is just a superficial mention. But it can be seen,TCE molecules put forward higher requirements for the double antibody platform.It not only needs to meet the coexistence of two antigen regions of general double antibody, avoid mismatch and realize the feasibility and efficiency of quantitative production; It is also necessary to comprehensively coordinate the affinity, binding kinetics, valence ratio, spatial position and other considerations of the two antigen arms, and require the platform to support more flexible and diverse molecular design.
At present, there are several dual-antibody platforms with independent intellectual property rights in China, each of which has its own advantages in molecular composition.. From the point of view of flexibility, HBICE platform of Platinum Pharmaceuticals and WuXiBody and SDArBody platform of Yaoming Bio have more advantages, which can realize symmetrical and asymmetrical modes and different valence collocation of the two arms (Table 3). Youzhiyou complements each other through two platforms: YBody and CheckBody. At the same time, these companies have also made small achievements in the field of CD3 double antibodies, such as CD3xClaudin18.2 licensed by Platinum Medicine to AstraZeneca, three TCE projects by Youzhiyou, and TCE projects of several companies by WuXiBody platform, with the fastest progress in clinical phase I..

Table 3: Common Double Antibody Platforms in China

03 BCMA related pipelines and transactions Valuable battlefields will never lack players.

Internationally, Pfizer Elranatamab has entered clinical phase III, Regeneron REGN5458 is in clinical phase II, and Abbvie ABBV-383 & HPN-217 and BMS CC-93269 are in clinical phase I. In the field of BCMA, domestic enterprises have made faster progress in cell therapy than TCE, and there are more players, such as Abcema, which has been listed abroad, Iqalunsei (CT103A), which is a cooperation between Reindeer and Cinda, which is now under NMPA listing approval, and Zewo Kirensei (CT053), which is planned to be submitted to NDA at the end of this year. In the field of CD3xBCMA double antibody, although domestic enterprises have some layouts, they are all in a relatively early stage. At present, the fastest progress is the shore biological, clinical I/II phase in the United States and Australia; Approved clinical enterprises include Shandong New Age, Connoa and Zhixiang Jintai under Lunan Pharmaceutical; Preclinical projects have been disclosed, including Platinum Medicine and Tianguangshi (Table 4). Table 4: domestic CD3xBCMA double antibody research projects

In response to its broad market potential, transactions related to BCMA have also appeared frequently in recent years.(table 5) It is worth noting that MNC may consider the layout of different molecular types, such as small molecules, antibodies or cell therapy, in order to consolidate its own pipeline competitiveness in the MM field. For example, Johnson & Johnson has CD38 monoclonal antibody, BCMA Car-T and CD3xBCMA monoclonal antibody, as well as CD3xGPRC5D monoclonal antibody and CD3xGPRC5DxBCMA monoclonal antibody in the pipeline under research; Abbvi introduced two molecules, Abbv-383B and HPN217, to a target of CD3xBCMA. In the field of cell therapy, the focus is gradually expanding from autosomal Car-T to heteromorphic Car-T, such as P-BCMA-ALLO1 of Poseida introduced by Roche in August this year.

Table 5: Overview of authorized transactions involving BCMA targeted therapy in recent 3 years

04 Let a hundred flowers blossom, the future can be expected!

At present, Abecma, Carvykti and Tecvayli have the same number of approved lines in the EU, all of which are four-line treatment (Table 1). Although Car-T may be cured, according to the current data, most patients will still relapse. Moreover, the current autologous cell therapy requires patients to wait in a professional treatment center for several weeks before receiving treatment to prepare Car-T cells, which may not only lead to the deterioration of the disease and fall off during the period, but also fail to achieve treatment because the cell quality is not up to the requirements. Therefore, under the condition that the curative effect is not far different and the number of approved lines is the same,As a "spot" drug, TCE has obvious advantages in terms of drug accessibility, cost and patient compliance.. In the United States, Tecvayli is still under BLA review, and the number of approved lines in the future deserves our attention.Whether it is antibody drugs or Car-T, the frontline expansion of indications is a battleground for military strategists.. Comparing ADC and Car-T as five-line therapy, if Tecvayli can move forward, the competitive advantage will be more prominent. In this regard, Car-T therapy also needs to further examine the effect of BCMA drug-resistant patients. Although BCMA is the most common target in R/R MM research, TCE double antibodies targeting CD38, FcRH5 and GPRC5D are also being explored, and even two tumor surface antigens are simultaneously bound by three specific antibodies in order to further improve the response rate and sensitivity. Some research projects include Johnson & Johnson’s CD3xGPRC5D and CD3xGPRC5DxBCMA, Ichnos Sciences’ CD3xCD38 and CD3xCD38xBCMA, Roche’s CD3xFcRH5, and CD3xBCMAxPD-L1 of CDR-Life.
This is an era when a hundred flowers blossom, and the Eight Immortals cross the sea and show their magical powers. Perhaps in the near future, the treatment of multiple myeloma can be similar to the management of chronic diseases, and even finally achieve cure.

Fast Technology reported on May 18 that a car blogger recently exposed a message for help from the owner of the 001. According to the owner, there was a problem with his car battery and he needed to replace it, which may be at his own expense.It will cost more than 100 thousand.

The owner of Extreme Krypton 001 said that he picked up his car in January this year and drove more than 3,000 kilometers. Due to business trip, he left home for two months, charged the car with 80-90% electricity before leaving, and then came back to drive, and found that the power battery of this car was broken because it had not been driven for a long time.

Because when I bought a car, I said that I had a lifetime warranty, and I asked about the after-sales. The other party said.Trams will break down if they don’t turn on their batteries, which is normal. It may be necessary to replace hundreds of thousands of batteries at their own expense..

Then the owner told some other experiences of his own, and the original words are given here, so as not to affect everyone’s judgment:

"I’m really glad to see everyone helping me so much. What I want to say is that this car company is really irresponsible. When an accident happens, it’s really all kinds of speculative responsibilities. I didn’t dare to reply to my sales service information, so I kept talking about looking for after-sales. I also want to contact the former employees of Extreme Neon if they have said anything to me.

There is no warranty for parking for 15 days below 20% of the electricity., unheard of. I have always driven a gas car. If this clause is common sense in driving a tram, car companies should emphasize it. Instead of talking about the terms when something goes wrong, 90% of the extremely chlorine sales staff don’t know. Although there are terms, it can’t be the reason for the insurance.

Many people ask, it’s incredible that the battery power drops so quickly, and they want me to contact the car company for inspection. Now I don’t know which battery pack of the power battery is broken after the extremely chlorine sale. Now I have to pay 5800 yuan for the inspection fee first. The reason is thatThere are no technicians of Weirui battery in Changsha, and the technicians have to come from other places and be responsible for his meals, accommodation and wages.I really laughed after listening to it. "

It is worth mentioning that in the user manual of Krypton 001, there is indeed a relevant explanation: "Damage or failure caused by the following reasons is not within the warranty scope", including exposing the vehicle to an environment above 50 degrees for more than 15 days; When the power battery is exhausted or about to be exhausted (less than 20%), the vehicle has not been used for more than 15 days.

In 2023, Chongqing’s automobile industry developed strongly, production and sales jumped, and key projects were successively effective, and the trillion-level intelligent networked new energy industry cluster continued to grow and develop. According to reports, from January to November 2023, the output value of Chongqing Intelligent Networked New Energy Automobile Industry Cluster increased by 8.3% year-on-year, and the automobile output reached 2.074 million, of which the output of new energy vehicles was 394,000, up by 23.6% year-on-year.

Standing at the node of the end of the year and the beginning of the year, "AUTO FUTURE Smart Friends Circle" compiled and launched "2023 Inventory: Key Projects and Industry Events of Chongqing Automobile Industry" to view the development context and opportunities of Chongqing automobile industry and look forward to the brand-new 2024.

01. The total investment is 10.6 billion yuan! Jiangxi Huanli Technology settled in Dazu.

On January 6th, Jiangxi Ring Lithium Project with a total investment of 10.6 billion yuan was signed and settled in Chongqing Dazu Economic Development Zone. The project covers a total area of 450 mu. After completion, it can realize the production lines of dismantling 100,000 new energy scrapped vehicles, handling 150,000 tons of retired batteries, utilizing energy storage modules (batteries) with an annual output of 2.5GWh step by step, and recycling battery-grade lithium hydroxide and lithium carbonate with an annual output of 30,000 tons.

02. With a total amount of 12.5 billion yuan, 12 automotive electronic industry projects were settled in Chongqing Economic Development Zone.

On January 10th, Chongqing Economic Development Zone held a special centralized signing ceremony for the automotive electronics industry, and signed 12 new projects with a total amount of 12.5 billion yuan.

Pengdao All-Vanadium Flow Battery Industry Chain Production Base is planned to be built in Chongqing by Pengdao New Energy Co., Ltd.; The production, R&D and application base of aerogel series products was built by Xizhi Future Technology Company with an investment of 1 billion yuan. The total investment of Zhixin Motorized Intelligent Networked Automotive AI Vision R&D and Production Base Project is 1.2 billion yuan; Chongqing Xiante intelligent equipment R&D and production base has a total investment of 1 billion yuan; Guodian science and technology western industrial base project plans to invest 3.5 billion yuan to build a new energy project operation center; The project of Keken New Energy Automobile Composite Material (Carbon Fiber) Parts Production Base plans to invest 500 million yuan;

And Minqiao PCP cloud native product collaboration platform, transportation city card green smart travel project, cloud network digital infrastructure service R&D and production base project, Aopu green light storage and charging smart charging and replacing power station integration and smart parking equipment and facilities base project, Xinghan smart chip R&D and manufacturing western base project and other projects settled in.

03. Ganfeng Lithium invested in Chongqing to build a power battery project with an annual output of 24GWh.

On January 19th, Ganfeng Lithium announced that its subsidiary Ganfeng Lithium planned to invest 10 billion yuan with Three Gorges Water Conservancy and Dongfang Xinyuan in Chongqing Fuling High-tech Zone to build a power battery project with an annual output of 24GWh. The product planning of the project includes lithium iron phosphate battery, ternary lithium battery and solid-state battery, BMS power management system development, battery R&D and testing center, as well as the assembly production line and related facilities with an annual output of 10GWh battery PACK.

04. Chongqing signed a strategic cooperation framework agreement with Huawei.

On January 30th, Chongqing Municipal People’s Government and Huawei Technologies Co., Ltd. signed a strategic cooperation framework agreement. The two sides will work together to build the industrial chain and ecology of intelligent networked electric vehicles, continue to deepen cooperation in artificial intelligence, smart cities, industrial Internet and digital transformation of enterprises, improve the cooperation promotion mechanism, and promote the sustainable development of Chongqing’s industrial transformation and upgrading and strategic emerging industries.

0.532 billion yuan! Jiangjin signed the new energy vehicle project of Dongfeng Xiaokang intelligent network connection

On February 8th, Jiangjin District of Science City (Shuang Fu Industrial Park) signed the new energy vehicle project of Dongfeng Xiaokang Intelligent Networking. The project plans to technically transform one of the production lines in Shuang Fu base of Dongfeng Xiaokang, upgrade it to a smart factory meeting the "Made in China 2025" standard, and develop and produce new energy vehicles. It is estimated that the transformation time will be one year. The project plans to invest about 3.2 billion yuan, which will form the production scale of high-end new energy vehicles with an annual output of 100,000-150,000 vehicles.

The 34th Annual Meeting of Chongqing Automobile Industry & Chengdu-Chongqing Automobile Technology and Supply Chain Expo was successfully held.

On March 21-23, Chengdu-Chongqing Automobile Technology and Supply Chain Expo was successfully held in Chongqing International Expo Center, and the 34th annual meeting and series of forums of Chongqing automobile industry were held at the same time. Around the theme of "Chengdu-Chongqing Twin Cities Economic Circle Cooperation Promotes Digital Transformation of Automobile Industry", more than 100 guests and more than 1,000 representatives from industrial and academic circles all over the country gathered together to discuss the digital transformation, transformation and upgrading of automobile industry, and help Chengdu-Chongqing Twin Cities Economic Circle to create a new ecology and reshape the industrial pattern.

Changan Automobile Exhibition Group, Sailisi Exhibition Group, SAIC Hongyan, Qingling Automobile, Chongqing Tongliang Exhibition Group, Faurecia, Pangang, Southwest Aluminum, Liangang, Yuntianhua Group, CITIC Branch Zhilian, Qin ‘an Shares, Yapu Shares, Sushi Yite, Sushi Test, Shimadzu, Leshan Radio, Horita Instruments, topview Instruments, and Electric Meter Trade.

It is reported that the next exhibition-2024 China Intelligent Electric Vehicle Technology and Supply Chain Exhibition (upgraded from Chengdu-Chongqing Automobile Technology and Supply Chain Expo) will be held in Chongqing International Expo Center on March 13-15, 2024, which will once again present a wonderful annual automobile feast.

07. The global R&D headquarters of Hesai Technology Software settled in Chongqing.

On March 26th, Chongqing Economic Development Zone signed an investment agreement with Hesai Technology for the project of the global R&D headquarters of Hesai Technology Software. According to the agreement, Hesai Technology will build a global R&D headquarters of Hesai Technology Software in Chongqing Economic Development Zone, set up an innovation incubation center, and build a lidar industrial park.

08. Celestial Group launched the new energy brand Blue Power.

On March 30th, Chongqing Sailisi Landian Automobile Co., Ltd., a subsidiary of Sailisi Group, officially released a brand new energy automobile brand-Landian. At the same time, it announced the official launch of its first model, Blue Power E5.

09. In the first quarter, Chongqing signed 10 major investment projects of intelligent networked new energy automobile industry.

On April 6th, the first quarter of investment promotion in Chongqing in 2023 was held with a centralized signing activity, and 70 major investment promotion projects were signed. Among them, there are 10 intelligent networked new energy automobile industry projects, such as T3 Travel Intelligent Networked West Headquarters and Wanbang New Energy Southwest Base, with a contract value of 31.7 billion yuan.

10. The intelligent production base project of new energy auto parts of Ruibiao Group was settled in Jiangjin.

On April 6th, the intelligent production base project of new energy automobile parts of Ruibiao Group with a total investment of 2.2 billion yuan was signed and settled in jiangjin district Luohuang Lingang Industrial City to help the development of Jiangjin new energy automobile industry. The project mainly produces new energy auto parts.

11. Yushi Technology Southwest Headquarters Project & Wanbang Star Energy Electrochemical Energy Storage System Advanced Manufacturing Base and Energy Internet Construction Project

On April 7th, the centralized signing activity of "Opening the Door" in the first quarter of investment promotion in Chongqing in 2023 was held. Western (Chongqing) Science City successfully signed two leading enterprises in the industry. They are: Yushi Technology (Beijing) Co., Ltd., the investment subject of Yushi Technology Southwest Headquarters and Passenger Car Intelligent Driving Business Headquarters, will build a regional headquarters and a national headquarters for passenger car intelligent driving business in the West (Chongqing) Science City around the application of driverless systems.

Wanbang Digital Energy Co., Ltd., the advanced manufacturing base of Wanbang Star Energy’s electrochemical energy storage system and the main investor of energy Internet construction project, will upgrade Wanbang comprehensive energy headquarters in Science City, and at the same time set up a new research and development project for energy storage batteries and energy storage systems, and plan to build an advanced manufacturing base with an annual output of 12GWh batteries and 3GWh energy storage battery systems.

12. Ganfeng lithium solid-state battery production base was built in Liangjiang New District, Chongqing.

On April 14th, it was reported that the largest solid-state battery production base in China, Ganfeng Lithium Industry Solid-state Battery Production Base, was put into construction in Liangjiang New District of Chongqing, with an annual battery capacity of 20GWh. The project will also build a solid-state battery research and development center and testing center in Liangjiang New District.

13. Tongliang Haichen Energy Storage signed three industrial chain projects with a total investment of 5.2 billion yuan.

On April 15th, Haichen Energy Storage officially released the "New Manufacturing" development plan, and signed four rounds of strategic cooperation contracts, including Haichen Energy Storage Strategic Customer Cooperation Contract, Syndication Contract, New Energy Storage Industry Development Demonstration Zone Cooperation and Construction Contract, and Energy Storage Industry Development Major Project Contract. Three upstream and downstream enterprises of Haichen Energy Storage Industry Chain, including Hebei Xingheng, Sichuan Jinhui Energy and Fujian Keda, settled in Tongliang with a total investment of 5.2 billion yuan. Project signing:

◆ The Chongqing production base project of aluminum foil for Hebei Xingheng battery has a planned total investment of 3.2 billion yuan. After the overall completion, it is estimated that the annual sales income will be more than 2.07 billion yuan, and the annual tax revenue will be about 113 million yuan.

◆ Sichuan Jinhuineng Lithium-ion battery anode material production base project plans to invest 1 billion yuan, with a planned land area of about 278 mu, to build a production base with an annual output of 100,000 tons of lithium-ion battery anode material. After full production, it is estimated that the annual output value will be about 3 billion yuan and the annual tax will be about 150 million yuan.

◆ The intelligent production project of lithium battery cathode material of Keda has a total investment of 1 billion yuan, and the planned land for the project is about 130 mu. The project plans to invest in the construction of an intelligent production line with an annual output of 50,000 tons of lithium battery cathode material. It is planned to achieve an annual output value of not less than 1 billion yuan and an annual tax revenue of about 55 million yuan.

It is reported that Haichen New Energy Southwest Intelligent Manufacturing Center and R&D Center project was signed in May 2022 and settled in Tongliang, with a total investment of 13 billion yuan. On December 7, 2023, Haichen Energy Storage Chongqing Manufacturing Base was officially put into production. After all the projects are put into production, the production capacity of 56GWh new generation energy storage lithium battery and 22GWh energy storage module will be realized.

14. Changan Automobile released the overseas strategy "All rivers run into the sea" plan.

On April 18th, Changan Automobile officially released its overseas strategy-"All rivers run into the sea" plan, and set the development goal of "Four Ones", that is, by 2030, the investment in overseas markets will exceed 10 billion US dollars, the annual sales volume in overseas markets will exceed 1.2 million vehicles, and the number of employees in overseas business will exceed 10,000, making Changan Automobile a world-class automobile brand.

15. Goer shares set up Zhixing Technology Company in Chongqing.

On April 24th, Goer announced the establishment of a company in Chongqing, which is named "Chongqing Goer Zhixing Technology Co., Ltd.".

16. Chongqing will build the largest refitting base for special vehicles in the west.

On April 26th, SAIC hongyan automobile Co., Ltd. signed a Strategic Cooperation Agreement with Chongqing Shuangqiao Economic Development Zone and China Highway Vehicle Machinery Co., Ltd. to jointly build the largest special-purpose vehicle refitting base and intelligent networked new energy automobile parts supporting base in western China.

17. The customized vehicle global headquarters base project of Tanfeng Intelligent Network Connection settled in Liangjiang New District.

On April 27th, Tanfeng Intelligent Networked Customized Vehicle Global Headquarters Base Project settled in Lianglu Orchard Port Comprehensive Insurance Zone in Liangjiang New District, and released a new model-Dongfeng Fengxing Tanfeng Diplomat, which was the first intelligent Networked Customized Vehicle Global Headquarters Base Project introduced in the comprehensive insurance zone. The total investment of the project exceeds 3 billion yuan, and the estimated annual output value exceeds 16 billion yuan.

18. Cool Wow Technology (Southwest) Headquarters Project settled in Yongchuan.

On April 27th, Yongchuan District signed an investment cooperation agreement with Kuwa Technology, and Kuwa Technology will invest 5 billion yuan to build the headquarters of Kuwa Technology (Southwest) in Yongchuan to build an industrial base of Kuwa self-driving function vehicles.

19. Coordinated development of intelligent networked new energy auto parts industry in western Chongqing.

On May 9, the General Office of Chongqing Municipal Government issued the Action Plan for Multiplying the Development of Intelligent Networked New Energy Auto Parts Industry in Western Chongqing (2023-2027), which clearly stated that the eight districts of Bishan, Yongchuan, Tongliang, Hechuan, Jiangjin, Tongnan, Dazu and Rongchang should coordinate their development and accelerate the construction of the national leading intelligent networked new energy auto parts characteristic industrial base. According to the Plan, by 2027, the scale of intelligent networked new energy auto parts industry in western Chongqing will be doubled, and the number of auto parts enterprises will reach 1,000, with an output value of 400 billion yuan.

20. Qingshan Industrial Ruipu Lanjun started the project of producing 30GWh batteries and PACK production base annually.

On May 9, Qingshan Industrial Ruipulanjun started construction of the 30GWh battery and PACK production base project. According to reports, the project was signed and landed in Fuling on February 24, 2023. The construction land area is about 763 mu, the total construction area is about 840,000 square meters, and the total investment is 10 billion yuan. The intelligent manufacturing production line of power and energy storage lithium-ion batteries with an annual output of 30GWh is laid out and the corresponding PACK production line is built.

21. Focus on "Internet of Vehicles+Industrial Internet" Qi Anxin’s dual headquarters is put into use in Liangjiang New District.

On May 19th, Qi ‘anxin Car Networking Security (National) Headquarters and Qi ‘anxin Industrial Internet Security (Western) Headquarters were put into use in Liangjiang New District with a total investment of 450 million yuan. At present, Chongqing Qi Anxin has established cooperative relations with Changan, Sailis, FAW, BAIC, BYD and other vehicle manufacturers.

22. Precision Forging Technology Chongqing "Automobile High-end Gear and Lightweight Key Parts Production Base Project" started.

On May 19th, Chongqing Pacific Seiko Technology Co., Ltd., a wholly-owned subsidiary of Precision Forging Technology, started construction in Yongchuan. The first phase of the project has a total investment of 600 million yuan, and it is planned to build high-end precision shaft and gear parts forging, machining, heat treatment, inspection and packaging workshops, aluminum alloy profile casting, aluminum alloy parts forging, etc. After the completion of the first phase of the project, it is estimated that the annual output value will be 900 million yuan.

23. Chongqing strives to build a "33618" modern manufacturing cluster system.

On June 5, Chongqing held a conference to promote the high-quality development of manufacturing industry, and formulated and implemented the Action Plan for Deepening the High-quality Development of Manufacturing Industry in New Era and New Journey in Chongqing (2023-2027). "33618" became the "new engine" for Chongqing to promote the high-quality development of manufacturing industry. Among them, it is proposed that Juli will build a trillion-dollar leading industrial cluster of intelligent networked new energy vehicles, a new generation of electronic information manufacturing industry and advanced materials.

24. The semiconductor giant will set up a factory in Chongqing with an estimated total investment of 29.8 billion yuan.

On June 8th, China’s leading compound semiconductor company Sanan Optoelectronics and international semiconductor giant stmicroelectronics (ST) announced at the same time that they would jointly build a factory in Chongqing for mass production of 8-inch silicon carbide (SiC) devices, with an estimated total investment of 3.2 billion US dollars (about 22.8 billion yuan). At the same time, Sanan Optoelectronics plans to set up a wholly-owned subsidiary in Chongqing to produce silicon carbide substrates as supporting facilities, with an estimated total investment of 7 billion yuan.

25. Infrastructure supporting project of intelligent networking new energy automobile industrial park in Longxing New Town, Liangjiang

Longsheng New City Intelligent Networked New Energy Automobile Industrial Park in Liangjiang New Area is one of the key projects in Chongqing, covering an area of about 2,875 mu and a construction area of about 927,000 square meters. It consists of workshops such as die-casting, stamping, painting and final assembly, and their supporting rooms, which will boost the development of Chongqing’s new energy automobile industry after completion. On June 9, according to Chongqing Liangjiang New District, the main structure of the industrial park project has been capped and will be fully completed and put into operation at the end of September.

26. Juwan Technology Research XFC Fast Rechargeable Battery Chongqing Base Project settled in Jiangjin.

On June 15th, jiangjin district and Guangzhou Juwan Technology Research Co., Ltd. held a signing ceremony, and Juwan Technology Research XFC Fast Rechargeable Battery Chongqing Base Project settled in jiangjin district. The total investment of the project is 7.2 billion yuan, covering more than 600 mu of land. The XFC ultra-fast rechargeable battery production base with an annual capacity of 16GWh will be built in two phases, and the annual output value is expected to be about 13.5 billion yuan after all the projects are completed.

27. Chongqing and Hisense Group will cooperate comprehensively in automotive electronics, display chips and smart cities.

On June 15th, the Chongqing Municipal Government signed a strategic cooperation agreement with Hisense Group, which will carry out all-round cooperation in three fields, namely, automobile electronics, display chips and smart cities, and actively explore the development of chips in the fields of building the China headquarters of Nippon Sandian Co., Ltd., the global R&D and manufacturing center for thermal management systems and key components of new energy vehicles, the intelligent technology industrial base in Sichuan and Chongqing, and IT display, vehicle display, new OLED display and vehicle control.

28. Dayang Electric New Energy Automobile Assembly Project settled in Yubei.

On June 19th, Dayang Electric’s "New Energy Vehicle Powertrain Project", a leading enterprise in the electric drive industry of new energy vehicles, officially signed a contract to settle in the frontier science and technology city of Yubei, and plans to build a production base and research institute. The total planned investment of the project is about 1 billion yuan.

29. Starr Semiconductor Chongqing Vehicle Gauge Module Production Base Project started.

On June 20th, Starr Semiconductor Chongqing Vehicle Gauge Module Production Base Project started. The total investment of the project is 400 million yuan. Starr will set up a holding company in Science City to invest in the construction of a production base for vehicle gauge modules. It is planned to use 40 mu of land to realize the research, development, production and sales of high-power vehicle gauge IGBT modules and vehicle gauge silicon carbide modules for the main controller, and it is planned to produce 1 million modules. A few days ago, Starr Semiconductor and Deep Blue Automobile established a joint venture company "Chongqing Anda Semiconductor Co., Ltd.", which will cooperate around the vehicle-class power semiconductor module.

30. Chongqing signed a strategic framework agreement with Geely Holding Group.

On June 21st, Chongqing Municipal People’s Government and Zhejiang Geely Holding Group Co., Ltd. signed a strategic framework agreement. The two sides will focus on building a world-class intelligent networked new energy automobile industry cluster, and further deepen strategic cooperation in the fields of new energy ecological construction, new energy automobile manufacturing, financial technology, industrial Internet digital platform, and automotive aftermarket business ecosystem.

31. Landay Technology: It is planned to invest 2 billion yuan to build new energy automobile parts and touch screen cover glass projects.

On June 25th, Lauder Technology announced that it had signed the Industrial Project Investment Contract with Chongqing Bishan High-tech Zone Management Committee, and reached a consensus on matters related to the construction of new energy automobile parts and touch screen cover glass manufacturing projects in Bishan District. The total investment of the project is 2 billion yuan, including the production line with an annual output of 4 million sets/piece of high-precision parts for new energy vehicles, and the production line with an annual output of 5 million pieces of on-board, industrial control, 3D glass cover plates and other related products.

32. North Star New Energy Vehicle LCD Project landed at Dadukou

On June 27th, Beixing New Energy Vehicle Car LCD Project was signed and landed in Dadukou, Chongqing. The project plans to invest 1.6 billion yuan for the research and development and production of customized cockpit display core domain controllers and related supporting products, including automobile instrument panel, central control panel and streaming media rearview mirror.

33. The total investment is 3.5 billion yuan! Aosong semiconductor project started.

On June 28th, the groundbreaking ceremony for the 8-inch MEMS characteristic chip IDM industrial base project of Aosong Semiconductor was held in the West (Chongqing) Science City. The total investment of the project is 3.5 billion yuan, and the land area is about 230 mu, including 8-inch CMOS+MEMS characteristic sensor chip mass production line, 8-inch MEMS characteristic wafer rapid research and development line, vehicle gauge sensor reliability testing center and other construction projects.

34. Lingxin (Chongqing) New Energy 20GWh Polymer Gel Solid State Battery Production Line Project & Ningbo Hongxie Automobile Lightweight Project

On June 29th, Changshou District held a centralized signing ceremony for key investment projects in June 2023. Among them, Lingxin (Chongqing) New Energy Co., Ltd. plans to invest 10.6 billion yuan to build a 20GWh polymer gel solid-state battery production line project; Ningbo Hongxie Co., Ltd. plans to invest 650 million yuan to build a lightweight automobile project.

35. Yongchuan centralized signed six projects, including automobile and motorcycle hub, automobile and motorcycle shock absorption, automobile glass and new energy commercial vehicle.

On June 30th, Yongchuan District held the second centralized signing of investment projects in 2023. Six new projects including automobile and motorcycle wheel hub, automobile and motorcycle shock absorption, automobile glass and new energy commercial vehicle were signed, with a total investment of 5.429 billion yuan. Among them, Taizhou Lushang Weilai Resources Holding Group Co., Ltd. invested 1 billion yuan in Yong’s construction of automobile and motorcycle shock absorption series, electric vehicle complete vehicles and supporting production projects, and Zhejiang Yulong Vehicle Co., Ltd. invested 500 million yuan to build intelligent manufacturing production projects of lightweight body parts.

36. The Radium Smart Lidar Project, Zhongde Forging Auto Parts Green Intelligent Manufacturing Upgrade Project and other projects have settled in Banan.

On July 5th, Banan District held a centralized signing activity for investment projects in the second quarter. Among them, some contracted projects involving intelligent networked new energy vehicles:

◆ The total investment of the Radium Smart Lidar Project is 488 million yuan, and it is planned to build a fully automatic factory, which mainly develops and produces 1550nm hybrid solid-state lidar.

◆ The total investment of Hongpusheng new energy vehicle high-voltage and low-voltage wiring harness production project is 50 million yuan, mainly to build a research and development and production base of high-voltage wiring harness for new energy vehicles, with an annual output value of about 100 million yuan after production.

◆ Haolong New Energy Automobile Plastic Products Upgrade Project plans to invest 410 million yuan, mainly to develop and produce fenders for new energy automobiles, and to carry out related technical services, technical consultation and technical support.

◆ Zhongde Forging Auto Parts Green Intelligent Manufacturing Upgrade Project plans to invest 450 million yuan to build a distributed photovoltaic power station and a distributed energy storage power station, and intelligently transform the existing 1000-ton press.

37.23 EB-PAC National New Energy Bus Performance Evaluation Competition was held.

From July 17th to July 21st, 2023EB-PAC National New Energy Bus Performance Evaluation Competition and China Bus Academic Annual Meeting were successfully held in China Merchants Automobile Research Institute of West (Chongqing) Science City. The evaluation competition was jointly sponsored by the Scientific Research Institute of the Ministry of Transport, Bus Branch of China Highway Society, Urban Passenger Transport Branch of China Road Transport Association, Management Committee of West (Chongqing) Science City and China Merchants Testing Vehicle Technology Research Institute Co., Ltd. (hereinafter referred to as "China Merchants Cheyan"), and undertaken by China Merchants Cheyan and Chongqing High-tech Development and Construction Investment Group Co., Ltd.

The theme of this evaluation competition is "helping the’ double carbon’ strategy and improving the quality of travel". As an important event in the field of new energy buses, 17 models from 11 bus companies in China compete fiercely around power consumption, driving range, acceleration time, wading safety, ride comfort (pulse input) and human electromagnetic protection.

38. The southwest headquarters of canoe Zhihang settled in Science City.

On July 20th, it was reported that the southwest headquarters project of canoe Zhihang was officially settled in the West (Chongqing) Science City recently. Qingzhou Zhihang plans to build its southwest headquarters in Science City, and lay out and build an autonomous driving operation service network platform, a business settlement center in Southwest China and an autonomous driving mass production R&D center (functions include autonomous driving algorithm and simulation R&D, etc.) to provide autonomous driving solutions and vehicle simulation products for vehicle manufacturers; Build a debugging, inspection, maintenance and maintenance base for self-driving bus vehicles, and deploy self-driving bus and taxi vehicles on the ground.

39. Intelligent Networked New Energy Vehicle Intelligent Chassis and Hybrid Power System Project & New Energy Vehicle Key Parts and Tooling and Mould Project

On July 31st, in the third quarter of 2023, a centralized signing activity for investment promotion of intelligent networked new energy auto parts was held, and Hechuan signed 23 intelligent networked new energy auto parts projects.

Among them, Kuntai Vehicle System (Changzhou) Co., Ltd. and Lvye Capital Group invested 6 billion yuan to build the intelligent networked new energy vehicle intelligent chassis and hybrid power system project, mainly building the national R&D center, production and marketing base of steering and braking system, the western production and marketing base of hybrid power system and flat wire motor, and the export platform with Chongqing base as the core.

Hangzhou Baowei Auto Parts Co., Ltd. invested 3.5 billion yuan to build a new energy vehicle key parts and tooling mold project, mainly engaged in the research and development and manufacture of auto parts molds, as well as automobile interior and exterior decoration, new energy vehicle battery tray, battery box cover and other production lines.

40. Development and production of millimeter-wave radar in Chengtai Science and Technology (Chongqing) Base started.

On August 5th, the development and production project of millimeter-wave radar in Shenzhen Chengtai Technology (Chongqing) Base started. The project is located in Chongqing High-tech Zone, with a total investment of 200 million yuan. After the project is completed, it will reach the annual production capacity of 8 million sets of millimeter-wave vehicle radar.

41. Tongnan signed a new energy project exceeding 7 billion yuan.

On August 22nd, Tongnan District of Chongqing signed a series of investment cooperation agreements with Gongjirun Road and Songdu Jiye, with an estimated total investment of over 7 billion yuan. According to the agreement, the two companies will invest in building four projects in Tongnan, including an annual output of 5GWH energy storage system and a new energy power battery smart factory equipment production base.

42. Sellers cooperates with Bosch China officially.

On August 24th, Celestial signed a strategic cooperation agreement with Bosch China. According to the agreement, the two sides will establish strategic cooperative relations in the fields of vehicle safety system, driver assistance, automation function, powertrain and electrification solutions, new material application and parts supply.

43. Changan Automobile released a brand new brand Qiyuan

On August 27th, Changan Automobile officially released the new energy intelligent brand-Changan Qiyuan. As a result, Changan Automobile has built three smart electric brand systems, namely, Changan Qiyuan, Deep Blue Automobile and Aouita, to meet the needs of different market segments.

According to reports, in 2023, the cumulative sales volume of Changan Automobile exceeded 2.55 million units, the sales volume of independent brand new energy exceeded 470,000 units, and the overseas sales volume of independent brands exceeded 230,000 units.

44.2023 Zhibo Fair was successfully held, and 19 major projects in the field of intelligent networked new energy vehicles were signed.

China International Intelligent Industry Expo 2023 was successfully held in Chongqing from September 4th to September 6th. On the afternoon of September 4th, a centralized signing activity was held for major investment projects of Zhibo Fair. Chongqing signed 84 major projects with a formal contract value of 213.86 billion yuan. Focusing on the annual theme of "Intelligent Networked New Energy Vehicles", this year’s Zhibo Fair promoted the signing of 19 projects in the field of intelligent networked new energy vehicles, with a formal contract value of 68.8 billion yuan, accounting for 32.2% of the total contracted amount. For example:

◆ Zebra Zhixing will use AliOS operating system as the traction to promote the construction of new auto parts industry chains such as intelligent cockpit and cockpit integration;

◆ PetroChina will cooperate with Aodong New Energy to build a commercial power exchange site to further enrich and improve the charging and power exchange scenarios in Chongqing.

◆ Konghui Automobile Layout builds a characteristic industrial cluster of air suspension, and extends an "olive branch" to Changzhou Shiqun Automobile and other related supporting enterprises;

◆ Ultra-fast charging industry ecological network project: The project investment is 10 billion yuan, led by the Jiulongpo District People’s Government, the state-owned platform company Yulong Group and Huawei Eco-Partners, and Huawei Digital Energy Technology Co., Ltd. is deeply empowered, which will create an ultra-fast charging brand "Chongqing second charging", allowing car owners to feel the ultimate charging experience of "one second and one kilometer".

◆ Hangzhou Weilan Creation Technology Co., Ltd. plans to invest 5 billion yuan in Bishan to build a national headquarters for the production and operation of zero-carbon green electricity transportation, including four business sectors, namely, R&D and manufacturing of heavy-duty battery packs for power exchange, R&D and manufacturing of complete sets of equipment for power exchange stations, operation center for power exchange stations and intelligent management platform, and successively build 10GWh sets of R&D and manufacturing bases for heavy-duty battery packs for power exchange stations.

◆ "Lihua New Energy Vehicle Intelligent Cockpit Production Base Project" in Yubei District: The total investment is 3 billion yuan, which is invested and constructed by Chongqing Lihua Genyuan Technology Co., Ltd., including 5 million sets of new energy vehicle digital LCD instruments, multi-screen linkage display system, HUD head-up display system, streaming media rearview and other products.

45. Guangdong Shilida 20 billion yuan energy storage project signed.

On September 12th, Guangdong Shilida Technology Co., Ltd. signed a project investment agreement with Tongnan, and the new power and energy storage battery production project with a total investment of about 20 billion yuan officially landed in Tongnan, Chongqing. The first phase of the project will invest 10 billion yuan, build 10 fully automatic production lines, and produce 26Gwh of new power and energy storage batteries annually. After all of them are put into production, the annual output value will reach 26 billion yuan.

46. The project of stator and rotor assembly of new energy automobile motor of CITIC Group was capped.

On September 17th, the production workshop of the new energy automobile motor stator and rotor assembly project of Zhixin Group, located in Longsheng New Town, Liangjiang New District, was capped. The project is a municipal key project with an investment of 1.31 billion yuan. It is expected to be completed in July 2024, and the R&D and production base with an annual output of 3 million new energy vehicle drive motors will be built.

47. Haowei New Energy Technology signed a project investment cooperation agreement with Tongnan.

On September 22nd, Guangzhou Haowei New Energy Technology Co., Ltd. signed a project investment agreement with Tongnan. Haowei New Energy plans to invest 10 billion yuan to build a production line project with an annual output of 30GWh solid-state square sodium ion battery in Tongnan District, and the annual output value will reach 42 billion yuan after all the projects are put into operation.

48. Western Science City signed three high-quality intelligent networked new energy automobile industry-related projects.

On September 28th, the centralized signing activities of key investment projects in Chongqing High-tech Zone of Western Science City in the third quarter of 2023 were held. The Science City signed three high-quality intelligent networked new energy automobile industry-related projects, including the Institute of Intelligent Testing and Equipment for New Energy Vehicles, with a total investment of 10.5 billion yuan.

49. Rongsheng Mengguli signed a contract with Tiantai Energy and Chongqing Aluminum Investment Group to lay out Jiulongpo District of Chongqing.

On October 9, Jiulongpo District held a centralized signing activity for key investment projects in the third quarter of 2023. As a major investment project in this signing, Rongsheng Mengguli joined hands with Tiantai Energy and Chongqing Aluminum Investment Group to sign a new flat-panel long-life energy storage battery production project. It is estimated that the total investment will be 2.3 billion yuan, and a new flat-panel long-life energy storage/commercial vehicle lithium iron phosphate battery production line with patented technology will be built. After the project is fully completed and put into production, the annual sales income will exceed 10GWh billion yuan.

50. China Merchants Cheyan was approved to build the National New Energy Vehicle Quality Inspection and Testing Center (Chongqing).

On October 11th, China Merchants Testing Vehicle Technology Research Institute Co., Ltd. announced that the State Administration of Market Supervision officially approved the establishment of the National New Energy Vehicle Quality Inspection and Testing Center (Chongqing). The successful approval of the center has filled the vacancy of the national quality inspection center for new energy vehicles without vehicle level in the western region of China, and is an important support for China Merchants Automobile Research Institute to arrange technical services for the whole industrial chain of new energy vehicles.

51. Changan Ford and Changan Automobile set up a new joint venture company to develop new energy sources.

On October 11th, Changan Ford New Energy Automobile Technology Co., Ltd. was formally established. This is another joint venture between Changan Ford and Changan Automobile, with a share ratio of 60% and 40% respectively. This new energy company intends to engage in the sales and service business of new energy passenger cars and existing Ford brand models of Changan Ford.

52. Catch up with 3 billion! Suzhou Lingchuang once again joined hands with Banan to enlarge and strengthen the intelligent networked new energy vehicle support.

On October 12th, Banan District, Chongqing held the third centralized signing activity of investment projects in 2023. Among them, Suzhou Lingchuang Group, which landed in Banan District in 2014, plans to invest an additional 3 billion yuan to build a high-end intelligent equipment innovation base of Lingchuang Technology of Science and Technology covering an area of about 150 mu. The project will introduce abundant capital and technical strength from Suzhou Lingchuang Group and Chongqing University of Technology, and build a domestic first-class intelligent networked efficient collaborative intelligent R&D and production platform, experimental testing platform and achievement transformation platform integrating new energy intelligent automobile assembly and key components, autonomous driving development platform, testing and analysis service center, database and high-end equipment manufacturing.

53. Bojun Technology: Chongqing subsidiary was established, and it is planned to invest 2 billion yuan to build the R&D and production base project of precision molds and auto parts.

On October 25th, Bojun Technology announced that it planned to sign the Project Cooperation Agreement with Chongqing Sharing Industry Investment Co., Ltd., and planned to build a research and development production base project for precision molds and auto parts in Shapingba District of Chongqing, with a total investment of about 2 billion yuan in total investment of the project, and set up a wholly-owned subsidiary, Chongqing Bojun Technology Co., Ltd. (incorporated on November 25th) to implement the investment, construction and operation of the project.

54. Lizhong Group High Performance Aluminum Alloy New Material Project

On October 26th, Shapingba District held the "Xingyao Shaci" investment attraction project in the third quarter of 2023, and Lizhong Group signed a contract for the new material project with an annual output of 100,000 tons of high-performance aluminum alloy. The total planned land area of the project is about 63 mu, with a total investment of about 600 million yuan. It will be built in two phases, with a planned construction capacity of 50,000 tons in the first phase. It will focus on the production and research of new energy vehicles, heat-free aluminum alloy materials for integrated die casting, high-performance aluminum alloy new materials and other products, and build an intelligent digital factory.

55. Deke Intelligent Steering System R&D and Production Base Project

On October 26th, Deke intelligent steering system R&D and production base project was signed and settled in Shapingba District. The total investment of the project is about 2 billion yuan, and the research and development production base of Deke intelligent steering system will be built, radiating Chongqing and Southwest China. At the same time, it is planned to engage in R&D and production of automobile steering system for the domestic vehicle market, and the products will be widely used in high-end intelligent driving passenger cars, smart city logistics, L4 autonomous parking service, commercial vehicles ADAS and other scenarios.

56. The new factory of Bosch Hydrogen Power System (Chongqing) Co., Ltd. was put into use.

On November 2nd, the new factory of Bosch Hydrogen Power System (Chongqing) Co., Ltd. was officially put into use. Located in Jiulongpo District, Chongqing, the project started construction in 2021, covering an area of about 240,000 square meters. It integrates R&D, testing, manufacturing and sales management of hydrogen power products, and is equipped with Bosch’s largest R&D center for Class A fuel cells (assemblies).

57. The total investment is 5 billion yuan! Solar energy automobile interior and exterior decoration system integration project settled in Yubei

On November 20th, Hangzhou Guangneng Rongneng Auto Parts Co., Ltd. invested and built the "Headquarters Base for Integrated R&D and Production of Automotive Interior and Exterior Decoration Systems" and signed a contract to settle in the Linkong Frontier Science and Technology City in Yubei District. The total investment of the project is 5 billion yuan, and the land area is about 121.7 mu. The products cover automobile interior and exterior decoration systems such as main and auxiliary instrument panel assemblies, front and rear door panel assemblies, front and rear bumper assemblies, front-end module systems and other functional structural parts for vehicles.

58. Invest 1.2 billion yuan! Beidou Navigation Quality Inspection Center (Chongqing Branch) Landing Beibei

On November 20th, Beidou Navigation National Quality Inspection Center (Chongqing Branch) signed a contract to land in Beibei Park of West (Chongqing) Science City. The project is invested and constructed by Beidou Future Big Data Technology (Beijing) Co., Ltd., with a planned investment of 1.2 billion yuan to build Beidou Navigation Quality Inspection Center (Chongqing Branch), land-based high-precision autonomous PNT system and intelligent networked automobile high-precision navigation and positioning and timing network respectively.

59. Tailan New Energy Chongqing Phase II Factory Project started.

On November 21st, Liangjiang New Area held the centralized commencement, completion and commissioning activities of the project in the fourth quarter of 2023. The second phase of Tailan New Energy Project, with a total investment of 1 billion yuan, officially started construction and is expected to reach production in 2025.

According to reports, the project covers a total area of 76 mu, with a construction area of nearly 50,000 square meters. It will build a semi-solid lithium battery cell production line and a semi-solid lithium battery PACK production line, with a planned production capacity of 2GWh, mainly to produce passenger car power batteries, taking into account the use scenarios such as small power and energy storage. It is estimated that the annual output value will exceed 2 billion yuan after reaching production.

60. Lilong Zhongbao Intelligent Cockpit Project started construction.

On November 21st, the Lilong Zhongbao Intelligent Cockpit Project invested by Chongqing Lilong Technology Industry (Group) Co., Ltd. officially started construction. The project has a building area of nearly 17,000 square meters, and mainly engages in the production, development and sales of AR-HUD, door controller DCU and electronic rearview mirror products. According to the plan, in the next five years, Lilong Group will invest 1.137 billion yuan for the construction of this project, and the factory building will be completed in March 2024.

61. The technical transformation project of intelligent production of high-voltage wire harness for Tianhai electronic vehicle was completed.

On November 21st, the high-end wire harness project of Tianhai New Energy Intelligent Network was officially put into production, and the total output value is expected to reach 5.5 billion yuan in the next five years. In May 2023, the project completed the factory renovation and equipment debugging, and has successively started the production and sales of high-end wiring harnesses and electronic products for new energy vehicles.

62. Changan Automobile’s "Golden Bell Hood" was released, and the first standard battery of Changan in Times rolled off the assembly line.

On November 17th, Changan Automobile released its self-developed battery brand-Golden Bell Hood at Guangzhou Auto Show, officially announcing its entry into the battery field. On November 24th, Time Changan Power Battery Co., Ltd., jointly established by Changan Automobile, Contemporary Amperex Technology Co., Limited and Deep Blue Automobile, officially ushered in the first battery product off the assembly line. This battery core is also one of the standard batteries of Chang ‘an golden bell jar battery.

63. Deep blue, Aouita and Qiyuan! Changan Automobile Announces Thailand Model Launch Plan

On August 23rd, Changan Automobile Thailand subsidiary was established. On November 8, Changan Automobile’s first overseas production base-Thailand manufacturing base was officially started. On November 27th, Changan Automobile brand launch conference was held in Southeast Asia, and then Changan Automobile introduced three digital intelligent product brands, namely DEEPAL Deep Blue, AVATR Aouita and NEVO Qiyuan, into the Thai market, and planned to launch 15 new energy products in the local area by 2030. In addition, Changan Automobile will also play Thailand’s "bridgehead" role in the Southeast Asian market and globalization strategy, and promote products and brands to radiate to Southeast Asia and the global right-hand drive market.

64. Chongqing launched the promotion of intelligent networked new energy auto parts industry.

On November 30th, the General Office of Chongqing Municipal People’s Government issued the "Chongqing Intelligent Networking New Energy Auto Parts Industry Cluster Promotion Special Action Plan (2023-2027)". The Action Plan proposes that by 2027, an intelligent networked new energy auto parts industry cluster with cross-domain integration, up-and-down coordination, mutual benefit and win-win situation will be built, and the operating income of Chongqing intelligent networked new energy auto parts industry will reach 700 billion yuan, with a total of 800 new intelligent networked new energy auto parts enterprises added.

65. Chongqing released the plan of "Chongqing Cars Going to Sea": By 2027, the annual export volume of complete vehicles will account for 10% of the national total.

On December 5th, the General Office of Chongqing Municipal People’s Government issued the Action Plan for Chongqing’s "Chongqing Cars Going to Sea". The Action Plan proposed that by 2027, the annual export volume of the whole city will account for 10% of the national annual export volume. Build 1-2 leading domestic intelligent networked new energy vehicle export enterprises and brands, and continuously improve the layout of overseas factories of enterprises; The intelligent networked new energy automobile industry has formed a strong international radiation capability, with an annual export value exceeding 120 billion yuan.

66. Landing of R&D and manufacturing projects of leading laser radar enterprises.

On December 15th, recently, the AME (Advanced Manufacturing Engineering) and vehicle-mounted laser radar R&D and manufacturing project invested by Tudatong officially signed a contract and landed in the West (Chongqing) Science City. The project will carry out process research and development, testing and manufacturing around laser radar, with an annual production capacity of 400,000 laser radars after production, which will drive upstream and downstream enterprises in the laser radar industry chain to gather and improve the local matching rate of auto parts.

67. Cyrus signed an agreement with Contemporary Amperex Technology Co., Limited to comprehensively deepen strategic cooperation.

On December 20th, Cyrus signed an all-round deepening strategic cooperation agreement with Contemporary Amperex Technology Co., Limited. The two sides will carry out in-depth cooperation in overcharge technology, battery safety, integrated development of "vehicle, electricity and charging" and big data, work together to expand overseas business and jointly promote battery technology innovation and global layout. Contemporary Amperex Technology Co., Limited will provide high-quality battery products for AITO series vehicles for a long time, and make deep cooperation in the research and development of new products, application of new technologies and new materials.

68. Changan Automobile has successively cooperated with Huawei, Weilai and Ganfeng Lithium Industry to expand the ecological circle.

Cooperation with Huawei: On August 17th, Changan Automobile and Huawei signed the Framework Agreement on Comprehensive and Continuous Deepening of Strategic Cooperation, and the two sides will cooperate in many aspects such as digital transformation. On November 25th, Changan Automobile and Huawei signed the Memorandum of Investment Cooperation, and Huawei plans to set up a new company focusing on intelligent networked automobile business.

Cooperation with Weilai: On November 21st, Changan Automobile and Weilai signed a cooperation agreement on battery exchange business to jointly promote the establishment of battery exchange standards, the construction and sharing of battery exchange networks, the research and development of battery exchange vehicles, and the establishment of an efficient battery asset management mechanism.

Cooperation with Ganfeng Lithium Industry: On December 22, Changan Automobile and Ganfeng Lithium Industry signed a Memorandum of Cooperation, which will accelerate the joint venture project of (semi-) solid-state battery research and development and industrialization project in accordance with the principle of "equal shareholding and efficient operation" and explore the deep cooperation between upstream and downstream of the battery industry chain. This cooperation is an important step for Changan Automobile to promote its "Shangri-La" new energy development plan.

69. Bosch Qingling hydrogen fuel cell engine project started.

On December 22nd, the commencement of Bosch Qingling Hydrogen Fuel Cell Engine Project was held in Jiulongpo District. The project is jointly built by Bosch (China) Investment Co., Ltd. and Qingling Group, and will build Bosch’s first research and development center for hydrogen fuel, a national production base for hydrogen fuel cell engines and a national production base for hydrogen energy commercial vehicles.

70. Zebra Zhixing Southwest Regional Headquarters and Smart Car Operating System Innovation Industry Cluster Project settled down.

On December 26th, Zebra Smart Car Operating System Co., Ltd. was established recently in Science Valley Digital Science and Technology Innovation Park, marking the official establishment of Zebra Zhixing Southwest Regional Headquarters and Smart Car Operating System Innovation Industrial Cluster Project in the West (Chongqing) Science City. The project will be based on Zebra Zhixing’s autonomous and controllable smart car operating system, and jointly develop, produce and sell new parts and components such as intelligent cockpit, intelligent driving and cabin driving integration with industrial partners.

71. With the listing of M9, AITO series products have repeatedly set new records in the industry.

On December 26th, Aito Wenjie M9, the flagship SUV of panoramic wisdom jointly designed by Celestial Automobile and Huawei, was launched, providing users with a continuous leading travel experience.

Sailis deeply practices the "Sailis model" of cross-border cooperation and builds a first-class intelligent electric vehicle brand through continuous forward-looking investment. Since the launch of AITO series products, it has continuously set a new record and ran out of the industry-leading "Sailis Speed". AITO asked the M9 to exceed 30,000 vehicles in the seven days since its listing; AITO asked the world that the new M7 has been listed for only three months, and the cumulative total has exceeded 120,000 vehicles, which has become a phenomenal event in the industry.

According to reports, from January to December, the cumulative sales volume of Celestial vehicles has reached 106,703, a year-on-year increase of 33.31%. In addition, on December 29th, Cyrus announced that it had obtained L3 autopilot test licenses in Chongqing and Shenzhen at the same time, becoming the only car company that has obtained L3 autopilot test licenses in both places at present.

72. Trial production of Kong Hui Science and Technology Southwest Production Base Project

On December 30th, the project of Konghui Science and Technology Southwest Production Base was put into trial production recently. The project was signed and settled in July 2023, with a total investment of 1 billion yuan. The southwest production base was built in the Western Science City, and five automobile air spring assemblies and electronically controlled suspension production lines were laid out. After the project is completed, it will fill the gap in the field of air suspension, a high-end core component of new energy vehicles in Chongqing.

73. The headquarters project of Puhua Intelligent Driving Basic Software Business was settled.

On December 31st, the project of Puhua Intelligent Driving Basic Software Business Headquarters was officially signed and settled in Science City. The project will be jointly invested by CLP Taiji Group, Puhua Basic Software Company and Chongqing High-tech Zone Management Committee with about 5 billion yuan. Puhua Zhijia Technology Co., Ltd. will be registered and established in the Science City, and it will be located in "one headquarters and two centers", namely, the intelligent driving basic software business headquarters, the national intelligent networked automobile basic software research and development center, and the domestic automobile electronic key software and hardware adaptation center, so as to build an intelligent network of "vehicle regulation chip+intelligent driving operating system+safe vehicle control operating system".

2024 China Smart Electric Vehicle Technology and Supply Chain Exhibition (referred to as "China Smart Electric Exhibition") is an innovative ecological platform for smart electric vehicles, which consists of exhibitions, conferences, supply and mining docking, technology release and industry selection. The exhibition is scheduled to be held in Chongqing International Expo Center from March 13 to 15, 2024. At the same time, the "Intelligent Electric Vehicle Science and Technology Ecology Conference", "The 35th Annual Meeting of Chongqing Automobile Industry", "Chengdu-Chongqing Intelligent Networking New Energy Vehicle Whole Parts Supply and Mining Docking Activity", "Chongqing Automobile Industry Annual Selection" and a series of forward-looking technical forums will be held.

The exhibition is co-sponsored by Chongqing Automotive Engineering Society, Chongqing Automobile Industry Chamber of Commerce, Chengdu Green Intelligent Networked Automobile Industry Ecosphere Alliance, Changan Automobile, Sailis, SAIC Hongyan, Changan Ford, Qingling Automobile, Ruilan Automobile, Changan Leap, etc. It is the first smart electricity eco-chain exhibition in China, which is built with the deep participation of automobile enterprises. The exhibition closely follows the global trend of automobile intelligence and electrification, gives full play to the leading role of "chain owner" automobile enterprises, and deeply presents the complete industrial chain of intelligent electric vehicles from design, materials, key parts of electrification, intelligent key technologies and digital intelligence to vehicle integration and application. Focusing on the four functions of "display, release, communication and procurement", we will build a one-stop interactive cooperation platform for new materials, technologies, products, new equipment, new supply chains and forward-looking technology products in the era of smart electric vehicles.

By then, it is estimated that 20,000 ㎡ exhibition area, 300+ global exhibitors, 1,500+registered delegates, 20+ theme forums and 20,000+professional visitors will attend the grand event. We sincerely invite global automotive eco-chain head enterprises and guests to participate in the grand event, gather in Chongqing and seek common future!

Recently, Christina Psaroudaki, a researcher at California Institute of Technology, and Christos Panagopoulos, a professor at Nanyang Technological University, put forward the idea of using Sigming as qubit, and said that it has advantages in practicality and scalability.

The research paper was published in Physical Review Express on August 4th, local time, titled "Skyrmion qubits: a new class of quantum logic elements based on nanometer magnetization".

"Quantum computing is expected to significantly improve computing power through the inherent characteristics of quantum mechanics, surpassing today’s supercomputers." In an exclusive interview with The Paper (www.thepaper.cn), Psaroudaki said, "Quantum computers are based on qubits, which are represented by the special quantum state of a physical system. Unlike the 0 or 1 of classical bits, quantum bits can also be in the so-called superposition state-that is, both 0 and 1. In order to realize quantum computers, many different candidates are currently being sought. "

The paper shows that the core of quantum computing is qubit made of very small particles such as atoms, ions or electrons. At present, superconducting circuit is one of the leaders of noisy medium-scale quantum computing scheme. Its size is macroscopic, but it has perfect quantum characteristics. Although superconducting quantum has made great progress, there are still great challenges, especially in control and scalability.

In magnetic materials, when the spin orientation of local atoms deviates, a quasi-particle with vortex structure will be produced, which is called magnetic sigmon. The properties of this quasi-particle can generally be described by topological charge or helicity.

"Sigmon has 1/2 spin, so it can be used as a qubit. Because of its good stability, controllability and measurability, it can be used as a logical qubit in quantum computing. The so-called logical qubit refers to the unit that can realize the function of qubit logically and consistently, and the physical deviation and failure probability have little influence. " Zhao Yukang, an industry expert of Guo Dun Quantum, told a reporter from The Paper (www.thepaper.cn).

"Magnetic Sigming can be very small, reaching the nanometer level, and it is a candidate for the next generation of information storage and logic technology. Magnetic Smirnology is a field that deals with the development of classical Smirnon spintronics, and it has developed into a huge and active research field. " Psaroudaki said, "An important feature of our proposal is to accelerate the development of Sigmund quantum bits by using the knowledge and the most advanced technology in the field of Sigmund. The knowledge and technology of Sigmund can be directly used and transferred to our proposed platform, and it provides advantages in practicality and scalability. "

Sigmon qubit

The scheme proposed by Psaroudaki and Panagopoulos is to realize qubits by using stable magnetic sigmons bound in magnetic nano-disks, and to connect different magnetic nano-disks by using electric fields.

By applying the electromagnetic field, the discrete energy levels in the quantized energy spectrum of the magnetic Sigmon can be controlled, so that the helicity between different energy levels can be changed, and these two energy levels can be encoded into two quantum states |0 > and |1 > of the qubit. In addition, the electromagnetic field can be tuned to control the coherence time of qubits. In this design, the quantum bits of adjacent magnetic nano-disks can also be coupled with each other, thus realizing two-bit quantum gate operation. Finally, the reading operation of quantum information can be completed by using a high-sensitivity magnetometer.

A member of the domestic quantum team gave a detailed introduction to the reporter of The Paper (www.thepaper.cn) on how the magnetic sigmoid in this research is used in quantum computation. He said, "This paper uses the quantum computation of the spin angle φ in the XY plane, a quasi-particle of magnetic sigmoid. According to the different parameters, it is divided into two bit theory designs. "

"The first is to encode the qubit state by using the deviation of the spin component in the z direction from the equilibrium state, and the deviation of 0 or 1 represents the 0 or 1 state of the qubit respectively. This design is similar to the charge qubit in superconducting bits, and the bit state is encoded by the number of charges on the island. The second is to encode the qubit state by using the rotation angle of spin in XY plane. The two angles in opposite directions represent the zero state or the one state of the qubit respectively. This design is similar to the magnetic flux bits in superconducting bits, and the quantum bits are encoded by clockwise and counterclockwise currents. " The member said.

Psaroudaki said that because the sigmons can be manipulated by electric and magnetic fields, the quantum bit properties of multiple sigmons are configurable and can be optimized. This includes logical qubit state and qubit lifetime, which are very important to realize stable and reliable qubits and can perform various logical operations. "Our work shows that the Sigmund quantum bit is very attractive as a logical element of quantum processor, and it is coping with the key challenges of quantum bit technology-control and scalability."

The paper shows that scalability, controllability of microwave field, operating time scale and non-volatile readout technology are all together, which makes the Sigmund qubit very attractive as a logic element of quantum processor.

At present, Psaroudaki and Panagopoulos have found several candidate materials, which can be used to design artificially adjustable magnetic Sigmon qubits. They predict that with the development of research, more materials will emerge in the future to realize this kind of magnetic sigmoid qubit.

When talking about the prospects and challenges of Sigmund in the field of quantum computing, Psaroudaki said, "Our work is at the intersection of two unrelated research directions-the quantum bit field and the Sigmund field. The former aims at developing quantum computers, while the latter aims at designing future spintronics devices based on magnetic Sigmund. Our idea has introduced a new direction in the field of Siegel electronics and nano-magnetism, and opened up an undeveloped way for quantum computing. The challenge now is practicality, that is, designing architecture for specific functions. "

"This paper constructs quantum bits on two-dimensional magnetic materials, which is really meaningful in physics and creates a new realization method of quantum computing. However, because this is a relatively theoretical article, the discussion of single-bit self-state, single-bit manipulation, inter-bit coupling and bit state reading still stays at the physical level, not at the actual design level. " The aforementioned members of the domestic quantum computing team said.

Zhao Yukang said, "The work of this paper is to experiment the logic gate manipulation ability of a single sigmoid, which is a new possible route of quantum computing, but there is still a gap from the realization, such as the coupling that has not been extended to multiple sigmoids, and the verification of the deterministic manipulation and long-term retention ability of logical qubits is not sufficient."

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