年度归档 2025年4月28日

Smile every day | Southerners spit out the makeup remover bought from the north into ice! Northerners domineering reply: This is really nothing.

In the digestive system of human body, "good" bacteria will produce a chemical substance that will change chromosomes in nearby cells. This discovery will help us better understand the relationship between diet and cancer.

The research team led by the British institute of Babraham found DNA in human colon epithelial tissue, which contains a special chemical that can be used as an epigenetic switch to turn genes on and off.

More importantly, the study found that in another part of the body, the brain, the content of these chemicals has also been increased.

Crotonylation is a recently discovered gene compilation process, which is different from a more common gene manipulation method called methylation. In both processes, the way of gene compilation has changed, by adjusting the surrounding chemicals, without changing the actual code itself.

Methylation is the addition of methyl (CH3) to nucleotides, usually cytosine (C), but occasionally adenosine (A), which transfers acetyl groups to histone proteins to keep DNA chains in order. The researchers found croton acylated histone in intestinal tissue, which shows that something really prevents cells from removing those acetyl groups. When the fiber of fruit in intestinal tract is fermented by microorganism, it will produce a micro-organic molecule called short-chain fatty acid (SCFA). Previous studies have shown that there is a connection between cell metabolism and croton acylation modification, and these short-chain fatty acids are the culprit.

The researchers analyzed tissues from colon, brain, liver, spleen and kidney, and found that there was a higher level of histone crotonylation modification in brain and colon. Why do these substances appear in the brain and not in other organs? This is still a mystery. However, this new study shows that it is bacteria that ultimately leads to this abnormal phenomenon. "Short-chain fatty acids are the key energy sources of intestinal cells, but we have also proved that they affect crotonylation modification of genome." Rachel from the Babraham Institute explained.

Intestinal bacteria are quietly changing our genes.

Specifically, short-chain fatty acid molecules produced by bacteria found in healthy human colon promote croton acylation modification by preventing an enzyme called histone deacetylase -2 (HDAC2) from removing labels. In order to prove that bacteria really work, the researchers set up a control group. They injected antibiotics into mice to destroy most of the bacterial flora in their intestines. Not only the content of short-chain fatty acids decreased, but also the crotonylation modification of histones in their intestines decreased.

This study may have some beneficial effects, such as knowing how human genes are affected by their own diet, which may help us to solve the relationship between diet and intestinal cancer to some extent. About 770 thousand people die of intestinal cancer every year in the world. Finding more ways to prevent and treat this disease is the first task of researchers.

At the same time, it also reminds us to pay attention to diet and ensure that not only our bodies get good nutrition, but also the smallest citizens in our bodies.

Patrick Varga-Weisz, the chief scientist of the study, said, "The intestines in the human body are home to countless bacteria.These bacteria help to digest food such as plant fiber, and they will also become a barrier to harmful bacteria and form our immune system.How these bacteria affect human cells is a key part of this series of processes.

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Race against time to release the kindness of doctors

Medical staff in the emergency department received emergency treatment.

As the first line to save lives, emergency medical staff are always ready to win the chance of survival for patients. Faced with the heavy task of treating critically ill patients and the risk of infection in the rescue operation, emergency patients did not hesitate at all. They went all out to interpret the doctor’s kindness with practical actions.

Today is the seventh "China Physician’s Day". We recorded the daily work status of the emergency department of Suzhou Municipal Hospital with a lens, in order to pay tribute to angels in white who is racing against time and guarding his life.

120 ambulance personnel quickly transported the patient.

From Chu Yang to twilight, and then from the dead of night to the dawn, the emergency department of the municipal hospital is always brightly lit. Outside the gate, the ambulance’s "beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep beep

At 8 o’clock in the morning, it was the hospital handover time. Cheng Renli, director of the emergency department of Suzhou Municipal Hospital, presided over the morning meeting of the department as usual, listened to the work reports of various departments and the patient’s situation, and reminded the medical staff of medical safety and drug use norms. After the morning meeting, everyone quickly returned to work. At this moment, a galloping ambulance outside the emergency room building stopped at the door, and four medical staff looked after the patient and rushed to the emergency room with an automatic stretcher.

Cheng Renli (first from right), director of the emergency department, leads the team to perform cardiac interventional surgery for patients.

When seeing a patient sent to the intensive care room, zhangqian, the nurse in charge, immediately greeted him, dressed the patient, covered the quilt, turned on monitoring instruments such as ECG monitor, assessed vital signs, established venous access, and then emergency doctors intervened and quickly started treatment.

"Whenever a patient who needs first aid is sent, we will first be treated according to different conditions, and those with mild symptoms will be sent to the emergency room, and those who are sent to the rescue room will be critically ill, and then we will evaluate the required diagnosis and treatment methods according to the patient’s situation." Zhangqian has 20 years of working experience in the emergency room, and this job has made her calm and calm. In her view, the urgent task of emergency room medical staff is to "save" and let critically ill patients "survive", followed by "diagnosis". "The diagnosis must be clear, the corresponding treatment plan must be clear, and then they will be admitted to the corresponding specialist clinic."

Acute myocardial infarction in emergency interventional surgery.

A heavy iron gate blocked the contact between critical patients in the emergency intensive care unit (EICU) and the outside world. A patient with a large-area fracture of the whole body has just been brought in. The rescue room has installed a neck brace, established a venous access and inserted a catheter for him. Wang Yuhang, a young male nurse in EICU, then took over the nursing work of this patient. The young man told reporters while making the bed for the patient: "My job is mainly to monitor the patient’s vital signs at all times after the doctor’s diagnosis, and clean up the body and treat the patient with drugs." In front of a critically ill patient’s bed, after examining the patient, Huang Chongjian, an emergency doctor, carefully told the medical staff around him about the current patient’s situation and warned the precautions for medication.

The critically ill patients were transferred from the intensive care room to the monitoring bed.

With the sound of "Didi, Didi …", the medical staff in the emergency room and EICU are fighting against the death for the patients. Wu Xinlong, who received the information from the 120 command center in the dispatching room, was also busy from the morning. On the two computer monitors in front of him, the page shows the order form of 120 in the north and south districts of the municipal hospital to pick up patients. The form is filled with information such as receiving orders, leaving the car, calling for help, and the reason for calling for help. Yang Yang, deputy director of the emergency department of the municipal hospital and director of the sub-station of the 120 municipal hospital, told the reporter: "On that day, 120 vehicles and 31 trips were dispatched from the two hospitals, and 172 emergency patients were treated. When the emergency department is not idle, it will also undertake some large-scale activities on the basis of daily rescue work. "

Observe the patient’s condition carefully.

In the emergency room, the reporter saw a group of people who robbed people with "death" and how people reborn hope in despair. Here, you can also see the life-and-death world, and you can see the mission and responsibility of medical staff.Text/Reporter Xu Leitu/Reporter Dong Muzi Special Photography Ma Yong


On the 30th, maintain the rainstorm red warning signal from day to night! Beijing’s Red Warning Response for Continuous Flood Control

  Cctv newsAccording to the latest forecast of Beijing Emergency Management Bureau and Meteorological Observatory, the tropical depression weakened by the typhoon and the warm and humid airflow around the subtropical high are combined. It is predicted that there will be heavy rain to heavy rain in Japan on the 30th, accompanied by easterly winds of grades 3 and 4 and gusts of grades 6 and 7. The rainfall in most parts of the city is 120~150 mm, and in parts of the west and south, it is 200~300 mm, with the maximum rainfall intensity of 50~80 mm/h. Affected by rainfall, the maximum temperature during the day will be around 25℃.

  Today, the rainstorm red warning signal is maintained from day to night, and Beijing continues to respond to the red (first-class) warning of flood control. The Beijing Flood Control Headquarters reminds the general public not to go out unless necessary. Enterprises and institutions, in addition to ensuring urban operation and people’s livelihood services, do not require employees to go to work unless necessary.

  From 09: 00 on July 29 to 06: 00 on July 30, the average rainfall in the city was 22.8 mm. The risk of secondary disasters such as mountain torrents, landslides, collapses and mudslides in mountainous areas and shallow mountainous areas is high. Please stay away from rivers and beware of floods, landslides and mudslides in the basin. Remind the public again not to go to mountainous areas, rivers and areas with hidden dangers of geological disasters, and not to drive in water; Don’t stay under tall buildings, billboards, temporary structures or trees during thunderstorms and strong winds.

Netease Cloud Music presented a song at the 20th anniversary of Netease, calling for Dad all the time.

[Text/Observer Network Zhuang Yi] This is a record company that has been delayed by enterprises and pigs, and there is no one.

On the occasion of the 20th anniversary of Netease, Netease Cloud Music specially launched "Ode to Netease’s Dad", reviewing Netease’s glorious history and sending blessings to one of the earliest Internet companies in China.

Whether it is lyrics, arrangement, singing or song cover, it can be called high-end atmosphere, low-key luxury and connotation. The catchy melody makes people unconsciously be substituted into it and hum softly, "Netease Dad ~"

It’s better to turn on the song and read the text

In a short time of 4:02, I sang the slogan that Netease Guangzhou is not easy to get rich, Netease News has an attitude, and the social intention of music.

Among them, the word "dad" appeared in the song for 10 times, which profoundly and vividly showed the gratitude and filial piety of the "good son" to his father, which was moving.

In addition, the beginning and the end echo, "I love work, and work makes me happy."Sing the voice of all office workers,"Overtime brings happiness"It is a wonderful experience that everyone can’t refuse.

It’s really gratifying to have such a "good son" ~

I love work, and work makes me happy.

Do you still remember the summer of memory?

The southeast coast of the motherland has a very developed economy.

My Netease father was in high spirits.

He started in Guangzhou with a unique eye.

Oh, bless dad. Bless dad

You are easy to surf the internet for the people.

This ideal, this great ideal

Take firm steps all the way

Ah, thank you, dad. Thank you, dad

(Please turn the page for excerpts of complete lyrics) …

That’s it? No, this song also has a companion piece-"Netease YEATION Refunds Money".

Please consciously bring in the tune of "cordate telosma" and hum it. Is it catchy?

There was an article a few days ago.

Dirt YEATION’s towel.

The boss said hum was super unpleasant.

Tell you what, the price will drop.

Is twelve yuan a strong one?

What should I do if I buy it before the price is reduced (what should I do ~ what should I do ~)

What about expensive users (what to do ~ what to do ~)

The boss said again, little fool

It’s easy. We’ll refund the money.

Every order is refunded.

Refund the money

……

On the anniversary, and then this song came out …

who let the pigs out!

(Who made Netease Weiyang pig? )

Ding Lei, Ding Lei, Ding Lei

who made the yanxuan

Who founded Netease YEATION? )

Ding Lei, Ding Lei, Ding Lei

Who let the pigs out!

(Who made Netease Weiyang pig? )

Ding Lei, Ding Lei, Ding Lei

Who play yun yinyue

(Who founded Netease Cloud Music? )

Ding Lei, Ding Lei, Ding Lei

Netease YEATION is one year old

Ding Lei said Yao Yao Da.

……

Next, even the recruitment has to sing a song crazily …

Please use "Yellow Crane, the son of a bitch boss, ran away with his sister-in-law" …

Zhejiang Hangzhou Zhejiang Hangzhou Netease Internet recruited.

Netease, a famous pig factory in Hangzhou, Zhejiang, has been recruited on the Internet.

Yun Music Cloud Classroom YEATION Koala Beishangguanghang Beishangguanghang

If you want to recruit, you have to recruit 1,800 people. When you see the demand, HR will be stupid.

We have no, no way, no way to do school recruitment by internal promotion.

All colleges and universities that originally wanted 985211 were exempt from screening.

No screening, no screening, no screening, no screening, no screening.

……

It’s enough for a record company delayed by an enterprise to sing without saying anything …

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Turn the page and enjoy the full version of fresh and unpretentious lyrics

Many districts in Beijing issued a yellow warning of strong winds, and trees were blown down due to strong winds.

Weibo screenshot

Weibo screenshot

  BEIJING, May 19 (Xinhua) According to the official Weibo news of Beijing Meteorological Bureau, on the afternoon of the 19th, Tongzhou District, Yanqing District, Changping District, Huairou District and Shunyi District of Beijing successively upgraded and issued yellow warning signals for strong winds. At present, gusts of magnitude 8-9 or above have appeared in some areas, and it is expected that there will still be gusts of magnitude 9 or above in the above areas by 22: 00.

  Due to security factors such as strong winds, the Asian Civilization Parade and the Asian Food Festival scheduled for this afternoon were cancelled.

  According to Weibo, the official news of the Capital International Airport, the Capital Airport has been affected by excessive crosswinds and windshear. Up to now, there are more than 20 alternate flights, which are expected to last until 19:00, and the traffic capacity has decreased.

  The Public Security Traffic Management Bureau of the Beijing Public Security Bureau also released a traffic report in its official Weibo: Fuchengmen Bridge on the West Second Ring Road is heading for the northwest ramp of Fuchengmenwai Street. At present, trees are blown down due to strong wind, which makes it impossible for vehicles to pass, reminding drivers in the past to take a detour in advance and pay attention to traffic safety.

  At about 14 o’clock today, the Beijing Meteorological Observatory issued a weather forecast: it will be cloudy (with showers in the north) and clear this afternoon, with northerly winds of 4 and 5, gusts of 7 and 8, and the highest temperature of 25 C; It is sunny and cloudy at night, with northerly winds of 3 or 4, gusts of 6 or 7, and the lowest temperature of 13℃.

  The Beijing Meteorological Observatory reminded that the north wind will blow hard today and tomorrow, so pay attention to wind protection and prevent falling objects from high altitude. The air is dry after the wind rises, so pay attention to fire safety.

It’s settled! What is Putin Trump’s meeting with Russia-US relations next month?

  CCTV News:Since Trump took office last year, Russia-US relations have not eased as expected, but the tension has intensified. Since March this year, the United States has gradually released information about possible meetings between the leaders of the two sides, but Russia has not made a clear statement. Until the 27th, Russia officially confirmed the news. On the 28th, Russia and the United States announced the specific time and place of the meeting.

  According to the release of Russia and the United States,The meeting between Putin and Trump will be held in Helsinki, Finland on July 16th. At that time, the two sides will exchange views on bilateral relations between Russia and the United States and other international hot issues.

  Putin: Russia-US relations are not at their best.

  In order to coordinate the leaders’ meeting, US Presidential National Security Assistant Bolton visited Russia on the 27th. When meeting with Bolton, Putin said that Russia-US relations are not at their best at present, which is largely the result of sharp political struggles in the United States. He hoped that Bolton’s visit would be a step towards a comprehensive restart of Russia-US relations.

  The United States frequently leaked the news, and the Russian side gave it a cold shoulder.

  For the summit meeting between Russia and the United States, the United States frequently let loose, while Russian officials handled it cautiously, even with some indifference. The Kremlin and the Russian Foreign Ministry have neither confirmed nor denied this plan before. It was not until Putin met with Bolton on the 27th that Russian officials said that the time and place of the Russian-US summit meeting had been confirmed.

  Just on the 21st of this month, Russian Foreign Minister Lavrov also said in response to a reporter’s question that "the upcoming Russia-US summit meeting" was deliberately leaked by the US, and Russia would not comment on this leaked news.

  Expert: It is difficult for the summit meeting to make a big turning point in Russia-US relations.

  As for the preparations for the summit meeting between the United States and Russia, analysts pointed out that the main purpose of planning the summit meeting is to prevent the highly tense bilateral relations from getting out of control and not to make a major turning point in Russia-US relations. Moreover, historically, US-Russian relations will experience a curve of "opening higher and going lower" after most new American presidents take office, from "restarting" in the early days of taking office to a sharp turn, and such plots have been staged repeatedly.

  Ups and downs! Russia-US relations are like riding a roller coaster.

  Due to Trump’s good comments on Russia during the campaign, it was once speculated that after Trump took office, the United States might reduce the pressure on Russia in order to achieve "breaking the ice" in Russia-US relations. However, this is not the case. Sometimes, the two sides are relaxed and sometimes tense. The wave of relations between the two countries is like a roller coaster.

  In July 2017, Trump and Putin met for the first time during the G20 Hamburg Summit.

  △ On July 7, 2017, during the G20 Hamburg Summit, US President Trump held bilateral talks with Russian President Vladimir Putin.

  US President Trump:

  President Putin and I discussed many things and had a very good talk. It was a very, very good talk.

  Russian President Vladimir Putin:

  We believe that Russia and the United States have good reasons and the two countries should reopen some cooperation.

  But a month later, Trump signed a bill to impose additional economic sanctions on relevant individuals and entities in Russia. Subsequently, the Russian side demanded that the staff of the US diplomatic mission in Russia be reduced, and the US side also demanded that Russia close the Consulate General in San Francisco and two diplomatic facilities in Washington and new york.

  There is a "minefield" in the relations between the two countries in eastern Ukraine on the Syrian battlefield.

  The Syrian issue and the situation in eastern Ukraine are all "minefields" where Russia-US relations are difficult to overcome. Both Trump and Putin have said that the two sides have communicated on this and "talked very well". But the moment of "talking well" is fleeting. On the Syrian battlefield, both sides and supporting forces claimed to be attacked by the other side. On the Ukrainian issue, the two sides have started a new round of angry words.

  The congratulatory message is not "full moon" and the United States "turns its face"

  In March this year, after Putin was re-elected as Russian president, Trump called to congratulate Putin and mentioned the possibility of meeting the two. But before the congratulatory message was sent out, he changed his tune again. On April 11, Trump posted a message on social networking sites warning Russia to get ready, and the new smart missiles of the United States will soon hit Syria. He also said that the current US-Russian relations are in the worst period in history, even worse than during the Cold War.

In ancient times, there were also outstanding great men with disabilities and strong will.

  In today’s society, there are countless people who are physically disabled and self-reliant, such as Zhang Haidi, Wu Yunduo and Tai Lihua … In ancient China, there are also many inspirational models. Some people’s contributions in a certain field even affect the development process of China’s history.

  Zuo Qiu’s blindness "Jue has" Mandarin "

  -Zuo Qiuming initiated the writing style of China’s history.

  Blindness is one of the important causes of disability in ancient and modern times. In ancient times, binocular blindness was called "blindness", "blindness" and "blindness", while monocular blindness was called "paralysis", also known as lateral blindness, and the former was commonly referred to as blindness.

  In the history of China, there are many celebrities with eye disabilities. For example, Shi Kuang, a famous musician in the pre-Qin period, was born without eyes, calling himself a "blind minister" and a "poor minister". Xia Houdun, a famous general called "The Wonder of the World" by Cao Cao in the Three Kingdoms, was called "Blind Xiahou" because he was blind in one eye. Cao Cao doesn’t discriminate against disabled people. He even married his favorite eldest daughter, qinghe princess, to the talented Rockett without one eye.

  Li Keyong, the legendary figure in the Five Dynasties and the great ancestor of the later Tang Dynasty, was also an eye-disabled person. Because he was born with one eye missing, he was named "Cyclops". In those days, Yang Xingmi, Huainan, had never seen Li Keyong, so he sent a painter to pose as a businessman to paint a portrait. When Li Keyong was informed, he wanted to embarrass the painter intentionally, so he arrested the painter to see how the painter painted himself. The painter was very clever, and he painted Li Keyong as a military strategist. Li Keyong was very satisfied with it. He not only let the painter go, but also gave him a lot of rewards.

  When it comes to inspiration, the most famous blind man is Zuo Qiuming, a great historian in the pre-Qin period and a blind man in Lu.

  Anyone who is familiar with Chinese scholars does not read Zuo Zhuan and Guoyu. The editor of these two important historical books in the pre-Qin period is Zuo Qiuming. The original name of Zuo Zhuan was Zuo’s Chunqiu, and later generations combined it with Chunqiu as an interpretation work, which was called Chunqiu Zuoshi Zhuan, or Zuozhuan for short.

  This book records some important historical events between the Zhou Dynasty and vassal states in 255 years, from the year of Lu Yin (722 BC) to the twenty-seventh year of Lu Aigong (468 BC). In addition to the importance of historical records, Zuo Zhuan also created the writing style of China’s historiography, which was highly praised by later historians and had a great influence on historians’ compilation of China’s history. For example, his "straight book without concealment" was inherited by the good history of China since Sima Qian, and became one of the basic principles of ancient history writing.

  Zuo Zhuan pioneered the format of "gentlemen say", which provided a space for historians to express their opinions. Since Sima Qian’s Historical Records, almost all the praises in the history books were inspired and influenced by Zuo Zhuan, so Zuo Qiuming was called "the founder of China’s traditional historiography".

  Guoyu, compiled by Zuo Qiuming, is the earliest national history of China, so it was named because it mainly recorded words. The book has 21 volumes, which respectively record the historical materials of eight countries, including Zhou, Lu, Qi, Jin, Zheng, Chu, Wu and Yue, from the end of the Western Zhou Dynasty to the Spring and Autumn Period (about 967 BC to 453 BC).

  When writing Mandarin, Zuo Qiuming was blind. Out of a sense of historical mission and responsibility, he recorded what he had seen and heard in the past decades, the important news of various governors and the gains and losses of the monarch and his subjects, and finally compiled and edited another China historical masterpiece. Sima Qian said in the preface to Historical Records Taishigong that "Zuo Qiu was blind and lost Mandarin", and that’s what happened.

  Not only did Zuo Qiuming’s Zuo Zhuan and Guoyu influence the study of China’s history, but his spirit of being physically disabled and striving for self-improvement was even more touching. Later generations directly referred to Zuo Qiuming as "blind history", which showed his respect for status and deep inspiration.

  Sun Tzu’s "On the Art of War"

  -Sun Bin’s Art of War influenced the ancient war behavior.

  Among the disabled people in ancient times, there were more physical disabilities than those who were blind, with the largest proportion of lower limb disabilities. In ancient Chinese, the words "limp", "limp", "limp" and "limp" all refer to lower limb disabilities.

  In ancient times, there were many celebrities with inconvenient legs and feet. For example, Bian He, who gave the famous Baoyu "He Shibi", is a disabled person who has lost both feet. Bian He’s disability is the acquired cause. According to "Everything is done wrong with him", when Bian He cut his salary on Jingshan Mountain, he occasionally got a rough jade, which was presented to King Li of Chu and Chu Wuwang successively, but the two kings didn’t know the goods, so Bian He was cut off his left foot and his right foot successively, which is called "Yesterday Bian He presented a treasure, and the king of Chu cut it off". Fortunately, King Wen of Chu knew the treasure and carved it into a world-famous "harmonious jade".

  Bian He’s feet were cut off, which is called "torture". The punishment of strangulation is one of the ancient tortures, which ranks among the "five punishments". The other four criminal laws are "Mo", "Mo", "Gong" and "Da Bi". Gouge, also known as chop, cuts off one foot, while the other cuts off both feet.

  Among the celebrities with lower limb disabilities in ancient times, the pre-Qin period was the most, which was because of the popularity of licking at that time. This punishment was abused to the climax in the Spring and Autumn Period and the Warring States Period. For Qi State when Qi Jinggong was in power, the most expensive prosthesis and the cheapest shoe were on the market at that time, which was the origin of the allusion of "being expensive and cheap" and the direct reflection of the social tragedy caused by Qi Jinggong’s abuse of the punishment.

  Sun Bin, a famous strategist in ancient times, was "gouged out" by Wei people before his death. However, he didn’t give in to his fate. After that, he won the trust of Tian Ji, the State of Qi, and set up an ingenious plan to command the army for many times, defeating Wei Jun, another rival and strategist led by Pang Juan, and forcing him to kill Pang Juan.

  Sun Bin, a native of Qi during the Warring States Period, was a descendant of Sun Wu, an outstanding strategist. Sun Bin studied the art of war with Pang Juan, and achieved excellent results. Later, Pang Juan was appointed as a general by Wei Huiwang. He thought that he was not as good as Sun Bin, so he set a deadly trap, tricked Sun Bin into going to Wei, and slandered him. Wei Huiwang, a fatuous man, committed a crime against Sun Bin, tattooed his face, and gouged out two kneecaps, which is the record of "cutting off his feet by law and punishment" in Biography of Sun Tzu Wu Qi in Historical Records.

  As a result, Sun Bin became a disabled person and could never stand up again. Pang Juan wanted to make Sun Bin "want to hide" and make him depressed from now on, but Sun Bin, who suffered a great blow, did not feel depressed, but lived stronger and more valuable.

  After Sun Bin was brought back to Qi by the envoys of Qi, Tian Ji was discerning and took in Sun Bin, and Sun Bin’s wisdom and courage were revealed. Tian Ji often shoots archery with the princes of Qi. Seeing that the upper, middle and lower third-class horses they use for racing are almost the same, it is difficult to win recklessly. So he came up with a clever plan: compare the worst horse with the best horse of the other side, compare the best horse with the average horse of the other side, and compare the average horse with the worst horse of the other side. After three races, Tian Ji won two and lost only one, which is the winning rule of "Tian Ji Horse Racing".

  Sun Bin’s outstanding military command ability and superhuman wisdom were brought into full play in the battles of "encircling Wei to save Zhao" and changed the historical trend of China at that time.

  Sun Bin later wrote his military experience and combat experience into a book, which is what Sima Qian called "Sun Tzu’s foot is fat, but not the art of war". Sun Bin’s Art of War was unearthed in Linyi, Shandong Province in 1974, which caused a sensation. The art of war is an important military theory in ancient times, which, together with the Art of War written by Sun Tzu, his ancestor, had a profound influence on China’s ancient military war behavior.

  Cai Hou’s paper "Everything is used in the world"

  -Cai Lun’s invention influenced the development of human civilization.

  Among the disabled in ancient times, people with physical defects were often ignored. In fact, the pain of these people is not less than that of other disabled people, but more hidden. The psychological damage suffered by them is more serious than the lack of legs and eyes, and some people even think that "life is worse than death."

  In ancient times, most celebrities with physical defects were acquired. The castration in the "five punishments" is an important reason for the great increase of people with physical disabilities in ancient times.

  The so-called "castration" is to destroy people’s reproductive function, "men are castrated and women are claustrophobic." Castration, also known as corruption, is second only to the death penalty. Originally called "lewd punishment", it was originally aimed at promiscuous incest men and women, and was later regarded as a criminal law, which was applied to prisoners. There is no humanity in the execution.

  Among the ancient celebrities with physical disabilities, Sima Qian, the author of Historical Records, is the most frequently mentioned.

  Sima Qian was a famous historian in the Western Han Dynasty. In the second year of Tianhan (99 BC), Sima Qian, who was 47 years old and was appointed as a Taishiling, said a few fair words when defending Li Ling, the general who attacked Xiongnu and failed to surrender, which angered Liu Che, the Emperor of the Han Dynasty, and was imprisoned. In the absence of money to atone for sin, Sima Qian "endured humiliation and lived, and asked for castration."

  Sima Qian was in agony after his imprisonment, but he thought that "King Wen was detained to play Zhouyi, while Zhong Nieu wrote Spring and Autumn Annals, and Qu Yuan’s exile was Li Sao". Sima Qian persisted and finally completed China’s first biographical Historical Records.

  Sima Qian’s deeds have undoubtedly become a typical example of inspiration. The group of eunuchs, a unique group of disabled people in ancient times, worshipped Sima Qian as a "grandfather".

  Eunuchs, also known as temple people and eunuchs, have emerged one after another throughout the ages. There are also many disabled celebrities with international influence in this crowd, such as Cai Lun and Zheng He. Among them, one of the most important and outstanding contributions is Cai Lun.

  According to "The Biography of Cai Lun in the Later Han Dynasty", Cai Lun entered the palace at an early age and became a eunuch. The Eastern Han Dynasty and Emperor Liu Zhaoshi were the constant attendants, and later he was ordered by Shang Fang. Although he is a disabled person, Cai Lun is ingenious and likes to make utensils and articles. After serving as an official order, he "supervised the secret swords and various instruments, all of which are exquisite and dense, which is the law for future generations".

  At that time, the writing materials of the court folk were mainly silks and bamboo slips, but the former cost was too high, and the latter was inconvenient to write and read. So Cai Lun improved the original paper-making technology of crushing hemp into fibers and extrusion molding at that time, and produced the earliest paper in the world that could be used for writing. In the 17th year of Yongyuan (A.D. 105), Cai Lun presented this batch of paper to Emperor Liu Zhao, and was praised by Liu Zhao. He specially named Cai Lun as "Longtinghou" and the paper he invented was also called "Cai Hou Paper".

  Since Cai Lun invented and improved papermaking, the world has made great contributions not only to China, but also to the development of human civilization.

  When "Cai Hou Paper" was widely used in China, expensive sheepskin and very brittle papyrus were still used as writing materials in Europe, so westerners listed papermaking as "Four Great Inventions" in China, and modern western scholars also ranked it as "the list of 100 celebrities who influenced the historical process of mankind".

  It should be noted that there are more disabled people in ancient China who have played an important role in the process of human history and civilization.

  (Ni Fangliu)

(Source: Beijing Evening News)

How to deepen the "focus" of medical reform and make the medical service system from "having" to "excellent"?

Xinhua News Agency, Jinan, July 30thQuestion: How to deepen the "focus" of medical reform and make the medical service system from "having" to "excellent"?

Xinhua News Agency reporters Dong Ruifeng and Li Zhihao

China’s average life expectancy has increased to 78.2 years, and it has built the largest basic medical security network in the world, and its main health indicators are in the forefront of middle-and high-income countries … For more than a decade, China has continuously deepened the reform of the medical and health system, and made efforts to solve the problem of people’s difficulty and expensive medical treatment.

At present, what are the key tasks for deepening medical reform? In what areas are ordinary people expected to continue to enhance their sense of gain? At the 2023 National Experience Promotion Conference on Deepening Medical Reform and China Health Development Conference held in Jinan, Shandong Province from July 29th to 30th, many industry experts took stock of the list of previous medical reforms and looked forward to the next stage "road map".

Can there be more quality medical services at home?

Promoting "serious illness can be solved in this province, common diseases can be solved in cities and counties, and headaches and brain fever can be solved in towns and villages" is an important goal of deepening medical reform.

At present, China has identified 125 national regional medical center construction projects, and the medical service "highland" covers all provinces with weak resources. In 2021, the first batch of inter-provincial medical treatment for related specialties of national regional medical centers decreased by 9.3% compared with 2019.

"The national regional medical center has basically completed the planning and layout, and the next step is to promote the establishment of a management system and operational mechanism that is compatible with it." Zhu Hongbiao, a first-class inspector of the System Reform Department of the National Health and Wellness Commission, said.

Balanced layout of high-quality medical resources, the level of diagnosis and treatment at the grassroots level is also constantly improving. By the end of 2022, 87.71% of county hospitals in China had reached the basic standard of medical service capacity, and more than 30,000 township hospitals and community health service centers had reached the standard of service capacity.

Zhu Hongbiao said that in the future, we will continue to plan and build provincial regional medical centers, continuously improve the medical level of cities and counties, strengthen the capacity building of community and rural medical and health services, improve the system and mechanism for promoting graded diagnosis and treatment, and promote the inheritance and innovation of Chinese medicine.

Focusing on the long-term, it is necessary to deepen the reform of public hospitals oriented to public welfare and develop and strengthen the medical and health team in order to let the people enjoy more high-quality medical services at their doorstep.

Previously, the national public hospitals have cancelled the addition of drugs and medical consumables respectively. How to consolidate the public welfare foundation of public hospitals, at the same time, ensure the source of salary of public hospital staff and mobilize the enthusiasm of medical staff has become an urgent task. "The next step is to continuously consolidate and improve the new operating mechanism." Zhu Hongbiao said.

How to reduce the burden of individual self-payment of ordinary people?

According to the latest funding standard of basic medical insurance for urban and rural residents in 2023, the per capita financial subsidy standard is 640 yuan per person per year. Ten years ago, this standard was 280 yuan.

Statistics show that in recent years, China’s government health expenditure and social health expenditure have continued to increase, and the proportion of personal health expenditure in total health expenditure has continued to drop to 27.7%.

"But the money that some ordinary people actually took out of their pockets for medical treatment did not feel significantly reduced." Xu Shuqiang, dean of China Hospital Development Research Institute of Shanghai Jiaotong University, said that an important reason is that the expenses beyond the reimbursement scope of basic medical insurance are still heavy.

On the one hand, we must continue to solve the problem of expensive medical treatment, on the other hand, the price of medical services is low, and some medical institutions have losses. How to solve the problem?

Not long ago, with the consent of the State Council, the National Health and Wellness Commission and other six departments jointly issued "Key Tasks for Deepening the Reform of Medical and Health System in the Second Half of 2023", which clearly proposed to promote the orderly connection of multi-level medical security.

Shanghai launched customized commercial medical insurance "Huhuibao" based on the rule of "employees in this city voluntarily use the surplus funds of medical insurance personal accounts over the years to purchase commercial medical insurance". In 2021, the number of insured people reached 7.39 million, and by the end of 2022, the accumulated compensation was 790 million yuan, which became an effective supplement to basic medical insurance and helped people to "reduce the burden" of seeing a doctor.

On the basis of realizing the full coverage of long-term care insurance for employees, Shandong Province started the pilot project of long-term care insurance for residents in 2022. At present, the number of long-term care insurance participants in the province has reached 41.12 million, ranking first in the country, which better meets the long-term care needs of severely disabled people.

Xu Shuqiang believes that deepening medical reform should not only make people spend less and less money from their own pockets, but also promote the development of public hospitals. We can consider more reform measures in which medical expenses are paid by third parties. While continuing to play the basic role of medical insurance fund, we will actively promote the development of inclusive commercial medical insurance, commercial health insurance and long-term care insurance.

How to "use good medicine" and "supply good medicine"

At present, a new round of medical insurance drug list adjustment is under way, focusing on children’s drugs and drugs for rare diseases.

In recent years, with the implementation of many measures, such as medical insurance drug catalogue access negotiation and centralized quantity procurement, 341 new drugs have been included in the catalogue at suitable prices, and the average price of centralized drugs has been reduced by more than 50%, saving about 300 billion yuan.

According to Jin Chunlin, director of the Shanghai Health and Healthy Development Research Center, the preparatory work for centralized procurement is more adequate, the scheme design is more rigorous, and the drugs and medical consumables that benefit the people are more abundant.

According to the data of the National Medical Insurance Bureau, centralized purchasing not only promotes the price reduction of drugs, but also makes the proportion of original drugs and drugs evaluated by the consistency of generic quality and efficacy exceed 90%, and the accessibility of high-quality drugs is greatly improved.

Support drug R&D and innovation, regularly carry out centralized procurement of drugs and medical consumables, strengthen drug supply guarantee and quality supervision … Focus on reform and innovation in the medical field, and a series of key tasks will be continuously promoted in the second half of this year to ensure "good supply of drugs" and "good use of drugs".

The relevant person in charge of the Department of Restructuring of the National Health and Wellness Commission said that this year, all provinces will be instructed to carry out centralized procurement of drugs and consumables at least once, and it is required to achieve a total of 450 drugs collected at the national and provincial levels before the end of the year.

In addition, it is understood that promoting the coordination and integration of medical care and prevention, promoting the reform of disease prevention and control system, and improving the capacity of public health services will also be important contents of deepening medical reform in the next stage, and a series of guiding documents are expected to be issued this year.

Grasping party member’s education management and playing a vanguard and exemplary role

Grass-roots Party organizations are the "nerve endings" of the whole Party organization, and party member is the "cell" of the Party organization. Only when the "cell" is of excellent quality and strong quality can the Party organization play its role as a fighting fortress. Strengthening education in party member is the fundamental measure to improve the quality of party member, and it is also an important content and way to strengthen the Party’s construction. How to strengthen and improve education in party member under the new situation is a problem worthy of our consideration.

Strengthen ideological education. With the deepening of reform and opening-up, it is urgent to further strengthen and improve education in party member under the new situation, and realize the transformation of educational thinking and the innovation of mechanism in party member. Efforts should be made to educate the party’s work style, party discipline, laws and regulations, and to train the knowledge of economy, modern science and technology and various practical technologies at different levels, so as to improve the practical working ability and skills of party member. Promote the development of various undertakings with pragmatic and rigorous style, enterprising attitude and excellent working ability.

Standardize educational management. To strengthen the daily management of party member, through regular education management constraints, construction, promotion, so that party member education management standardization. By paying attention to the daily typical propaganda, we will promote the formation of a good atmosphere of seeing Si Qi and striving to be a pioneer, so that party member can give full play to its advanced nature. At the same time, with the accelerating trend of "all things are intelligent, all things are connected, and all things are counted", we should make full use of the advantages of new media, such as convenient communication, diverse forms, wide audience and strong interaction, keep up with the pace of the times, innovate party member’s educational management concept, find a good combination of work, and constantly enhance the pertinence, foresight and effectiveness of party member’s educational management to help the party building work take root and blossom.

Pay attention to the unity of knowing and doing. Party member’s education management should be practical and focused on implementation. Let party member be strong in the front line, weather the storm and see the world. Through education management, Party organizations will be extended to the front line, resources will be integrated into the front line, services for the people will be carried out in the front line, and difficult problems will be solved in the front line. In the aspects of grassroots social governance, promoting the work of "party building+letters and visits" and helping scientific and technological innovation, party member education management will be integrated into service practice, and the education management in party member will be "last mile" to serve the masses.

Grasp the daily supervision. "Impurity" in party member’s ranks under the new situation puts forward new requirements for the comprehensive and strict administration of the Party. It is necessary to carry out targeted party spirit education and warning education, and strengthen clean government education in party member. Through criticism and education, honest talk, etc., "biting the ear and pulling the sleeve, blushing and sweating" has become the norm, and party member who has problems should be reminded as soon as possible, and early attention should be paid to prevention, and no accommodation will be tolerated. (Qiao Kun)

Source: Party and Mass Work Department, Dianchi Resort, Kunming

Experts’ Interpretation of Wild Robot: Predictive Edition of "AI Parenting"?


Special feature of 1905 film network Adapted from overseas best-selling books, the movie with the dreamy animation team escorted was released nationwide on September 20th. The film tells the story of Rose, a robot living in the wilderness, who unexpectedly becomes the "temporary guardian" of Dayan Xiaobudian. When the established program meets the disorderly wilderness, the motif of love and growth emerges.



This issue invites film critic Zhou Guiyi to talk about this animated film full of "chicken soup for the soul". Is it worth drinking?


Watching movies for all ages, 2024 family fun animated film!


The film is ahead of the overseas release, and has won good reputation and evaluation among the audience. Many viewers said that this is the most worthwhile animated film in their hearts in 2024, and the film critic Zhou Guiyi felt the same way and gave the film an evaluation of 8 points.



"Wild Robot" can be said to be the most family-friendly film this year. First of all, it is visually well done. The story background of the film is in a "wasteland era", but there is no darkness and decadence in the whole film. On the contrary, it presents a large number of natural landscapes in a fresh and hand-painted state, which is very close to the temperature sense that the film wants to express.



Secondly, the theme of the story is also deep. In the film, the robot Rhodes plays a powerful mother with logic, speed and strength, but it will still be confused when facing the problem of parenting. If a person becomes a mother, even the robot will suffer internal friction.



In addition, the film also pays attention to the topic of the growth of young people at present, and discusses how to judge the sense of individual belonging. In the film, Rose is a robot wandering in the wilderness, separated from the robot group, and the weak wild goose is also an alien, raised by a robot from birth, and it has no way to blend in with the geese; After watching the film, you may have a new understanding of the word "belonging". Whether belonging is collective, family or blood depends on what kind of identity and role you are substituting.



Brand-new robot image, the next animation?


As we all know, many animated films produced by DreamWorks have impressive images, such as Shrek, Puss in Boots, Po Panda, Toothless Boy, Crazy Primitive Man and so on, all of which are from DreamWorks. This time, Robot in the Wild created the first animated robot image. What are its differences?



Not as cute as Eva and Kawara Tsutomu, and not as soft as Libai, but after watching the movie, we will find that the advantage of robot Rose is its appearance. The director’s settings let the audience see that this is an era of mass production robots, which keeps its rough and simple appearance and has a good contrast with its perfect personality.


In the past, the robot seemed to be naturally set as a male character, but the voice and emotional mode of Rose and the encounter with the wild goose in the film all pointed out that it was a woman, which combined the height of maternal love and humanity with the coldness of the robot. In the past robot movies, we were all thinking about the direction of human and machine AI, which was a confrontational relationship, but when the robot became a woman, it seemed to find a way to coexist.


In the movie, Rose puts all the animals in a warm cave, which is a biological chain that kills each other in the laws of nature. But now all species have to spend this cold winter first, and Rose has established an ideal state of harmony in the world and replaced it with the brilliance of motherhood.



However, some viewers also gave different views on the role of Rose, thinking that "the role is added with passive mother’s love and responsibility, acquiesced in her female identity and deliberately sensationalized"; Others say, "Sure enough, a mother’s duty is a never-ending task". Will the mother’s setting make this story appear rigid or thin?


In this regard, Zhou Guiyi said, "I personally don’t want to wrap the movie characters in such an overly feminist environment, and then interpret them in an overly binary way." I believe that the richness of the movie, Rose was a responsible person and a server from the day she was born, but she just happened to meet a weak life, which inspired an emotion similar to maternal love.



Many settings on Rose are not aimed at geese. The audience should not be too sensitive to think that the tenderness on Rose is a strong setting that must be disciplined as a mother for female identity, but should see that there is a great love beyond maternal love from a female perspective.



New thinking on human destiny in AI era


It seems to be a perfect story and a perfect character, but many viewers think that the film is old-fashioned, too preaching, and the setting of a happy ending that breaks the food chain is too idealistic. A bowl of chicken soup for the soul that is too rich may not achieve the desired effect.



However, Zhou Guiyi disagreed with this view. "I don’t think it is a particularly rich chicken soup, but I think this classic traditional expression has time continuity." Wild Robot is about the new survival law in the AI ? ? era. Robots have a lot of big data, and they can purify themselves with logic and constant algorithms. Animals live by instinct and experience, so when they meet, they will definitely collide with some different sparks.



The movie "Wild Robot" uses a simple way to tell the audience that "kindness is the ultimate way to survive". When AI and robots come in the future and the values before human order are subverted, what else is worth believing? Maybe we can find some answers in this film.